Max Konig
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maxkonigmd.bsky.social
Max Konig
@maxkonigmd.bsky.social
350 followers 140 following 12 posts
Rheumatologist/ Assistant Prof at Johns Hopkins | Director, Cellular Therapy Program (Autoimmunity) | Advancing precision immunotherapies for autoimmune diseases (https://www.koniglab.org). 🇩🇪🇺🇸
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maxkonigmd.bsky.social
Not the first one treated. I believe on of the early SLE patients with CNS disease treated by iCell in China did very well.
December 5, 2024 at 3:01 AM
maxkonigmd.bsky.social
Thank you❤️
November 17, 2024 at 7:17 PM
maxkonigmd.bsky.social
Not sure who had the terrible idea to put up our talks on TRBV9 at the same time but in different rooms. No chance for debate. @acr-journals.bsky.social not good planning.
November 17, 2024 at 6:33 PM
maxkonigmd.bsky.social
acrabstracts.org/abstract/t-c...
T Cell-Engaging Bispecific Antibodies to Target Autoreactive 9G4 Idiotope B Cells in Systemic Lupus Erythematosus - ACR Meeting Abstracts
Background/Purpose: Chimeric antigen receptor (CAR)-T-cell therapies hold promise for systemic lupus erythematosus (SLE) but are critically limited by scalability and long-term safety (e.g., risk of t...
acrabstracts.org
November 17, 2024 at 4:37 PM
maxkonigmd.bsky.social
acrabstracts.org/abstract/pre...
Precision Targeting of Autoreactive 9G4 B Cells in Systemic Lupus Erythematosus Using Engineered Chimeric Antigen Receptor (CAR)- and Chimeric T Cell Receptor (cTCR)-T Cells - ACR Meeting Abstracts
Background/Purpose: The autoreactive B cell compartment in systemic lupus erythematosus (SLE) is characterized by expansion of B cells expressing immunoglobulin heavy variable gene 4-34 (IGHV4-34) B c...
acrabstracts.org
November 17, 2024 at 4:36 PM
maxkonigmd.bsky.social
acrabstracts.org/abstract/trb...
TRBV9-Targeted Bispecific T Cell-Engaging Antibodies to Reset the Autoreactive T Cell Compartment in Spondyloarthritis and HLA-DQ8 Celiac Disease - ACR Meeting Abstracts
Background/Purpose: Therapies that indiscriminately deplete all T cells carry a high risk of opportunistic infection, precluding their widespread use in T cell-mediated autoimmune diseases. Targeting ...
acrabstracts.org
November 17, 2024 at 4:35 PM
maxkonigmd.bsky.social
Has anyone ever claimed CAR-T cell therapy is a cure-all?
November 12, 2024 at 2:58 PM