The Maurer Lab
@maurerlab.bsky.social
Understanding biology to improve gene therapy. Opening Jan 2025! University of Michigan Department of Biophysics. https://maurerlab.org
Reposted by The Maurer Lab
We are thrilled to announce the 2025 Leading Edge Fellows! 40 outstanding postdoctoral fellows doing pioneering research in a wide range of biological and biomedical disciplines.
Learn more about these exceptional scientists:
www.leadingedgesymposium.org/fellows
Learn more about these exceptional scientists:
www.leadingedgesymposium.org/fellows
May 27, 2025 at 4:57 PM
We are thrilled to announce the 2025 Leading Edge Fellows! 40 outstanding postdoctoral fellows doing pioneering research in a wide range of biological and biomedical disciplines.
Learn more about these exceptional scientists:
www.leadingedgesymposium.org/fellows
Learn more about these exceptional scientists:
www.leadingedgesymposium.org/fellows
Glad to share this finally! We explored how modulating host factors could improve dual rAAV vector transduction. Key takeaways: HDR inhibition boosts expression & concatenation, and transient HDRi enables lower doses & higher efficiency! More to come in the Maurer Lab.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Double-strand break repair pathways differentially affect processing and transduction by dual AAV vectors - Nature Communications
AAV vectors are a promising gene delivery vehicle but have a limited DNA packaging capacity. Here, the authors identify cellular restriction factors whose temporary inhibition significantly enhances t...
www.nature.com
February 14, 2025 at 2:10 PM
Glad to share this finally! We explored how modulating host factors could improve dual rAAV vector transduction. Key takeaways: HDR inhibition boosts expression & concatenation, and transient HDRi enables lower doses & higher efficiency! More to come in the Maurer Lab.
www.nature.com/articles/s41...
www.nature.com/articles/s41...