Matthew Amsden
matthewamsden.bsky.social
Matthew Amsden
@matthewamsden.bsky.social
CEO, Efforia
At Efforia, we’ve completely reinvented the clinical trial model — making it possible for innovators outside traditional healthcare to generate real evidence. This allows non-traditional treatments to stand on equal scientific footing with those from big pharma and major medical centers.
October 30, 2025 at 12:21 AM
Is the real gap in healthcare not access, but proof and ROI?
Seems to me this is a massive opportunity for new leaders to break out by showing how their therapies have real ROI ... whether its' a nutritional supplement or consumer medical device.
Leveraging Health Care Price Transparency
A purchaser-driven analysis combining hospital and payer pricing data with purchaser claims data and quality metrics reveals the promise of current transparency regulations for health care purchasers and the areas of opportunity for policymakers
members.pbgh.org
October 28, 2025 at 11:47 PM
Hospitals aren’t just where we go for care—they’re where most people work.
Boston, Houston, LA, NYC, Bangor, Joplin… in many cities, the largest employer is the hospital.
If healthcare employs millions, can it ever truly change without economic shock?
October 28, 2025 at 10:54 PM
The US innovation ecosystem is the best on earth—but if we don’t get housing, childcare, and healthcare costs under control, it’ll become nearly impossible to build the next generation of great companies.
The Average Cost of a Family Health Insurance Plan Is Now $27,000
The cost of health insurance rose steeply for a third year in a row in 2025, reaching just under $27,000 for a family plan, according to an annual survey from the nonprofit KFF, which provides the broadest picture of U.S. employer health coverage. That is a 6% increase from the year before, and builds on two prior years of 7% gains. The cost is rising faster than inflation, and economists and business leaders said it could bite into employment and wage growth.
www.wsj.com
October 27, 2025 at 11:17 PM
Radiologists just debunked one of AI’s biggest myths: automation doesn’t always mean elimination. it often expands demand. When scans become faster and cheaper, hospitals do more of them. Efficiency created more capacity — and more need for humans in the loop.
October 27, 2025 at 10:14 PM
The next winners in health won’t be the ones with big budgets. They’ll be the ones who rethink what "proof it works" means. Because if history tells us anything, it’s that industries rarely fall to those who can outspend them — they fall to those who outlearn them.
October 23, 2025 at 11:07 PM
Will today’s longevity skeptics look like the travel agents who warned us not to use Expedia—or the stockbrokers who swore E*Trade would fail?
October 21, 2025 at 11:47 PM
AI, predictive analytics, & digital twins are revolutionizing how we run clinical trials—boosting efficiency, scalability, & speed. I'm all in. But I keep coming back to one question: As we push more decisions onto patients are we underestimating how deeply people distrust statistical inference?
October 21, 2025 at 10:54 PM
Nearly a decade and countless investments in clinical trial innovation later, the core truth remains: nothing has changed. It’s time to rethink what’s possible. The future starts with breaking down barriers to who can run trials.
Why The Research Community Should Heed The Warnings of This Election
Why The Research Community Should Heed The Warnings of This Election
www.huffpost.com
October 20, 2025 at 11:17 PM
As enterprise customers, how do we make sure our valued vendors consider our concerns — without rushing to boycotts? That question’s been on my mind since reading this morning about Salesforce’s reported interest in supporting ICE Agent recruitment efforts.
www.nytimes.com/2025/10/16/u...
October 20, 2025 at 10:14 PM
Real and meaningful innovation in clinical trials isn’t happening where you think. It’s happening at a vitamin company a spa Or a small business that never imagined it could run a clinical trial before.

Here’s why 👇
October 15, 2025 at 3:27 PM
Efforia is launching a multi-site trial - not in hospitals or academia, but in Light therapy studios. After all, clinical trials shouldn’t be limited to pills you can ship—or to hospitals you’ll hopefully never have to visit.

app.efforia.com/greenlight-t...
October 14, 2025 at 10:54 PM
It's beyond fixing nutritional gaps. “Formulas” are replacing vitamins because people are looking for solutions: to optimize, prevent, and even treat everything from minor skin irritations to chronic conditions.
October 14, 2025 at 3:25 PM
Efforia is launching a multi-site trial - not in hospitals or academia, but in Light therapy studios. After all, clinical trials shouldn’t be limited to pills you can ship—or to hospitals you’ll hopefully never have to visit.

app.efforia.com/greenlight-t...
October 13, 2025 at 11:17 PM
Every major innovation looks ridiculous… until it doesn’t: could that include longevity bro-science? What if the process of creating evidence doesn't have to follow the traditional CRO clinical trial model?

lnkd.in/ecBwne_z
THE TOP 20 LONGEVITY INFLUENCERS OF 2025: REDEFINING WHAT IT MEANS TO AGE WELL
We used to think growing older meant something slowing down—less energy, less clarity, and the creeping inevitability of decline. But in 2025, a vibrant, global scene is flipping that narrative: a…
lnkd.in
October 13, 2025 at 10:14 PM
Clinical trials don’t just need good science. They need great logistics.
I still get excited when an Efforia package arrives at my door.
Because I know how complex the technical and operational logistics are to get it there.
October 9, 2025 at 8:55 PM
There’s an inconvenient truth about “convenient” lab testing from Function Health and Oura Ring. 👇
October 9, 2025 at 12:21 AM
For many wellness founders, their first experiment wasn’t a pharma trial
It was an effort to find a solution for their own problems👇
October 7, 2025 at 11:47 PM
Founders often learn more from leadership missteps than from legends like Steve Jobs.
Here are 4 lessons on leadership I’ve been reflecting on after this week’s Defense Department meeting 👇
October 6, 2025 at 4:53 PM
We don't just need more research; we need more research literacy. Research literacy involves understanding these nuances, learning to interpret results, evaluate evidence strength, and recognize subtleties overlooked by sensational headlines.
October 4, 2025 at 12:03 AM
We’re launching a study with Neuphoria, the brain EEG measurement device, and the Monroe Institute. This study explores how objective EEG data—beyond self-reported outcomes—can capture the real impact of cognitive enhancement practices and treatments.
Cracking Consciousness Study with Monroe & Neuphoria (Cohort III) | Join Study at Efforia
You've explored the Monroe Focus levels. But, Bob Monroe said, “You might believe something, but you won’t understand it until you can measure it with objective data.” Now, for the first time, we can…
app.efforia.com
October 3, 2025 at 12:48 AM
Good things come to those who persist with consistency.
Little comes to those who just wait.
October 2, 2025 at 11:07 PM
Trust in health seems broken, with skepticism spanning across political lines, affecting faith in science & research results. In this "post-trust" era, clinical trials, when conducted differently, can offer measurable, individualized results, moving beyond cultural debates.
October 2, 2025 at 1:40 AM
Can clinical trials be made interesting and relevant to a manosphere audience more interested in sex and dating. In public health there's a concept of meeting people where the are at - as I did by guesting on the Access Vegas podcast. Response was quite positive.
www.youtube.com/watch?v=zejS...
Are WOMEN Taking the RED PILL now? @StirlingCooper
THE RATIONAL MALE ➜ https://www.amazon.com/stores/Rollo-Tomassi/author/B00J2165RA REIGNITE ➜ https://reignitealpha.com MOA MENTORING ➜…
www.youtube.com
October 2, 2025 at 12:21 AM
Efforia has introduced a feature for treatments that show immediate effects. Instead of assessing long-term use, it focuses on immediate differences, like using a sleep aid one night and skipping it the next - comparing treatment vs. non-treatment days, capturing episodic effects
September 30, 2025 at 11:47 PM