Matteo Calcagnile
@matteo-calcagnile.bsky.social
A molecular microbiologist at the University of Salento, passionate about nature, and bioinformatics enthusiast...
Neisseria meningitidis uses the methylcitrate cycle to detoxify propionate. Carbon sources and bicarbonate influenced propionate toxicity. Mutants lacking prpB/C are sensitive to propionate, and kbuT enables uptake of α-ketobutyrate.
#IDSky #Microbiology #microsky #mevosky
#IDSky #Microbiology #microsky #mevosky
November 13, 2025 at 8:53 AM
Neisseria meningitidis uses the methylcitrate cycle to detoxify propionate. Carbon sources and bicarbonate influenced propionate toxicity. Mutants lacking prpB/C are sensitive to propionate, and kbuT enables uptake of α-ketobutyrate.
#IDSky #Microbiology #microsky #mevosky
#IDSky #Microbiology #microsky #mevosky
We found that Pirin, a redox-sensitive modulator of β-oxidation in Streptomyces, generates radicals as a signal to activate antioxidant systems and interacts with CatR, the repressor of catalase
Evolutionary conservation of redox crosstalk?🔬✨
www.sciencedirect.com/science/arti...
Evolutionary conservation of redox crosstalk?🔬✨
www.sciencedirect.com/science/arti...
Pirin, a redox-sensitive modulator of beta-oxidation, generates hydroxyl radicals and interacts with CatR, the transcriptional repressor of the major vegetative catalase gene in Streptomyces
Pirins are iron-containing proteins conserved throughout evolution, which have been implicated in diverse cellular processes, mostly associated with s…
www.sciencedirect.com
September 6, 2025 at 7:03 PM
We found that Pirin, a redox-sensitive modulator of β-oxidation in Streptomyces, generates radicals as a signal to activate antioxidant systems and interacts with CatR, the repressor of catalase
Evolutionary conservation of redox crosstalk?🔬✨
www.sciencedirect.com/science/arti...
Evolutionary conservation of redox crosstalk?🔬✨
www.sciencedirect.com/science/arti...
We found that Pirin, a redox-sensitive modulator of β-oxidation in Streptomyces, generates radicals as a signal to activate antioxidant systems and interacts with CatR, the repressor of catalase
Evolutionary conservation of redox crosstalk?🔬✨
#mevosky #EvoBio #MicroSky
doi.org/10.1016/j.mi...
Evolutionary conservation of redox crosstalk?🔬✨
#mevosky #EvoBio #MicroSky
doi.org/10.1016/j.mi...
August 28, 2025 at 10:11 PM
We found that Pirin, a redox-sensitive modulator of β-oxidation in Streptomyces, generates radicals as a signal to activate antioxidant systems and interacts with CatR, the repressor of catalase
Evolutionary conservation of redox crosstalk?🔬✨
#mevosky #EvoBio #MicroSky
doi.org/10.1016/j.mi...
Evolutionary conservation of redox crosstalk?🔬✨
#mevosky #EvoBio #MicroSky
doi.org/10.1016/j.mi...
🌱 PFOA alters soil microbial communities, boosting K. grimontii and C. braakii, both carrying antibiotic resistance genes and virulence factors.
📈 PFOA increases resistance gene transcription, raising concerns about soil as a reservoir for AMR pathogens.
#PFAS #microbiomesky #Microbiology #MicroSky
📈 PFOA increases resistance gene transcription, raising concerns about soil as a reservoir for AMR pathogens.
#PFAS #microbiomesky #Microbiology #MicroSky
Per- and polyfluoroalkyl substances (PFAS) as environmental drivers of antimicrobial resistance: insights from genome sequences of Klebsiella grimontii and Citrobacter braakii isolated from contaminat...
Per- and polyfluoroalkyl substances (PFAS) are man-made chemicals widely used for industrial applications since the 1940s. PFAS are extremely persistent in the environment, to the extent that they hav...
doi.org
July 16, 2025 at 10:25 AM
🌱 PFOA alters soil microbial communities, boosting K. grimontii and C. braakii, both carrying antibiotic resistance genes and virulence factors.
📈 PFOA increases resistance gene transcription, raising concerns about soil as a reservoir for AMR pathogens.
#PFAS #microbiomesky #Microbiology #MicroSky
📈 PFOA increases resistance gene transcription, raising concerns about soil as a reservoir for AMR pathogens.
#PFAS #microbiomesky #Microbiology #MicroSky
Reposted by Matteo Calcagnile
1/46 Hey folks, we have a new paper out on the MuLTEE. Strap in and I’ll tell you the story of how this “little paper on polyploidy” turned into the most data rich paper our lab has produced, largely thanks to the leadership and work ethic of @kaitong25.bsky.social.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Genome duplication in a long-term multicellularity evolution experiment - Nature
In the Multicellularity Long Term Evolution Experiment, diploid yeast evolve to be tetraploid under selection for larger multicellular size, revealing how whole-genome duplication can arise due to its...
www.nature.com
March 5, 2025 at 11:00 PM
1/46 Hey folks, we have a new paper out on the MuLTEE. Strap in and I’ll tell you the story of how this “little paper on polyploidy” turned into the most data rich paper our lab has produced, largely thanks to the leadership and work ethic of @kaitong25.bsky.social.
www.nature.com/articles/s41...
www.nature.com/articles/s41...