Máté Manczinger
@matemanc.bsky.social
Group leader of the Systems Immunology Research Group at HUN-REN Biological Research Centre, Szeged, Hungary
C > U mutations generate immunogenic peptides in SARS-CoV-2
APOBEC enzymes—key players of the innate immune system—induce mutations that become fixed in viral genomes and enhance immune recognition.
nature.com/articles/s41...
#COVID_19 #Immunology #virus #infectiousdiseases #vaccine #Genetics
APOBEC enzymes—key players of the innate immune system—induce mutations that become fixed in viral genomes and enhance immune recognition.
nature.com/articles/s41...
#COVID_19 #Immunology #virus #infectiousdiseases #vaccine #Genetics
C > U mutations generate immunogenic peptides in SARS-CoV-2 - Nature Communications
The effect of new viral mutations on T cell responses remains unclear. Here, Balogh et al. show that most new mutations in SARS-CoV-2 are C > U, a bias that leads to an enhanced T cell re...
nature.com
December 1, 2025 at 5:48 PM
C > U mutations generate immunogenic peptides in SARS-CoV-2
APOBEC enzymes—key players of the innate immune system—induce mutations that become fixed in viral genomes and enhance immune recognition.
nature.com/articles/s41...
#COVID_19 #Immunology #virus #infectiousdiseases #vaccine #Genetics
APOBEC enzymes—key players of the innate immune system—induce mutations that become fixed in viral genomes and enhance immune recognition.
nature.com/articles/s41...
#COVID_19 #Immunology #virus #infectiousdiseases #vaccine #Genetics
Reposted by Máté Manczinger
C > U mutations generate immunogenic peptides in SARS-CoV-2 @natcomms.nature.com @matemanc.bsky.social
@csabapallab.bsky.social
www.nature.com/articles/s41...
@csabapallab.bsky.social
www.nature.com/articles/s41...
November 19, 2025 at 4:23 PM
C > U mutations generate immunogenic peptides in SARS-CoV-2 @natcomms.nature.com @matemanc.bsky.social
@csabapallab.bsky.social
www.nature.com/articles/s41...
@csabapallab.bsky.social
www.nature.com/articles/s41...
Reposted by Máté Manczinger
I C U mutant!
Our new paper is out! Our immune system doesn’t just fight viruses – it edits them.
APOBEC enzymes introduce C>U mutations that often make viral proteins easier for HLA molecules and T-cells to detect, boosting immune recognition.
nature.com/articles/s41...
#COVID_19
Our new paper is out! Our immune system doesn’t just fight viruses – it edits them.
APOBEC enzymes introduce C>U mutations that often make viral proteins easier for HLA molecules and T-cells to detect, boosting immune recognition.
nature.com/articles/s41...
#COVID_19
November 25, 2025 at 7:53 AM
I C U mutant!
Our new paper is out! Our immune system doesn’t just fight viruses – it edits them.
APOBEC enzymes introduce C>U mutations that often make viral proteins easier for HLA molecules and T-cells to detect, boosting immune recognition.
nature.com/articles/s41...
#COVID_19
Our new paper is out! Our immune system doesn’t just fight viruses – it edits them.
APOBEC enzymes introduce C>U mutations that often make viral proteins easier for HLA molecules and T-cells to detect, boosting immune recognition.
nature.com/articles/s41...
#COVID_19
I C U mutant!
Our new paper is out! Our immune system doesn’t just fight viruses – it edits them.
APOBEC enzymes introduce C>U mutations that often make viral proteins easier for HLA molecules and T-cells to detect, boosting immune recognition.
nature.com/articles/s41...
#COVID_19
Our new paper is out! Our immune system doesn’t just fight viruses – it edits them.
APOBEC enzymes introduce C>U mutations that often make viral proteins easier for HLA molecules and T-cells to detect, boosting immune recognition.
nature.com/articles/s41...
#COVID_19
November 25, 2025 at 7:53 AM
I C U mutant!
Our new paper is out! Our immune system doesn’t just fight viruses – it edits them.
APOBEC enzymes introduce C>U mutations that often make viral proteins easier for HLA molecules and T-cells to detect, boosting immune recognition.
nature.com/articles/s41...
#COVID_19
Our new paper is out! Our immune system doesn’t just fight viruses – it edits them.
APOBEC enzymes introduce C>U mutations that often make viral proteins easier for HLA molecules and T-cells to detect, boosting immune recognition.
nature.com/articles/s41...
#COVID_19
www.pnas.org/doi/10.1073/...
How cancer arises: Genetics releases, plasticity creates, genetics stabilizes
How cancer arises: Genetics releases, plasticity creates, genetics stabilizes
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
September 22, 2025 at 5:24 PM
www.pnas.org/doi/10.1073/...
How cancer arises: Genetics releases, plasticity creates, genetics stabilizes
How cancer arises: Genetics releases, plasticity creates, genetics stabilizes