Selma Masri
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masrilab.bsky.social
Selma Masri
@masrilab.bsky.social
190 followers 190 following 21 posts
Associate Professor @UC Irvine studying how circadian clocks impact immunity, metabolism, stemness, and cancer. Obsessed with wine and my plants.

https://masrilaboratory.com
Posts Replies Media Videos
Reposted by Selma Masri
cosimocommisso.bsky.social
Excited to share work published in @cp-cancercell.bsky.social by @yijuan.bsky.social showing that macropinocytosis inhibition drives myCAF-to-iCAF conversion, enhancing therapeutic responses in pancreatic cancer. Thank you to our collaborators that contributed! www.sciencedirect.com/science/arti...
Macropinocytosis maintains CAF subtype identity under metabolic stress in pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) tumors are glutamine deficient, and both tumor cells and cancer-associated fibroblasts (CAFs) rely on this ami…
www.sciencedirect.com
July 24, 2025 at 5:49 PM
Reposted by Selma Masri
drstarbird.bsky.social
"Nature has learnt that … some staff members are screening candidates’ social-media presences to check whether they have expressed negative views about the Trump administration or been involved in diversity, equity and inclusion (DEI) efforts … at their institutions."

www.nature.com/articles/d41...
Exclusive: NIH to dismiss dozens of grant reviewers to align with Trump priorities
The move would undo years of work, leaving advisory councils understaffed, and without the full expertise needed for reviews.
www.nature.com
July 15, 2025 at 2:04 PM
Reposted by Selma Masri
jeremymberg.bsky.social
Science story about termination of terminations...

www.science.org/content/arti...
Following court order, NIH ceases new terminations of politically sensitive grants
After a judge told agency to restore hundreds of killed grants, NIH backs off plans to cancel more existing projects
www.science.org
June 25, 2025 at 7:36 PM
Reposted by Selma Masri
pannunziolab.bsky.social
A number of firsts this year including my first time participating in commencement @ucirvine.bsky.social and hooding my first 2 graduate students that have earned their PhDs!! Congratulations Valeria and Melissa! You are both amazing and this is only the beginning! 💪🧬🧪🦸‍♀️🦸‍♀️
June 24, 2025 at 1:47 AM
Reposted by Selma Masri
jeremymberg.bsky.social
The findings at the recent trial and today's Columbia chaos is pushing me to the edge.

I just sent the following email...
June 18, 2025 at 7:29 PM
Reposted by Selma Masri
jeremymberg.bsky.social
Here is a link you can blast out to all of your networks to ask them to consider signing on in support of our NIH heroes.

actionnetwork.org/forms/add-na...

We are at 5000 folks who have signed on. But we can do better

Only for people who have ever been sick or knows someone who has been.
ADD YOUR NAME: Sign the Open Letter in Support of NIH Staff
Join the courageous and committed National Institutes of Health (NIH) public servants by adding your name now.
actionnetwork.org
June 9, 2025 at 7:38 PM
masrilab.bsky.social
Looking forward to sharing our recent work at #SLEEP2025! Circadian Medicine session starting in about an hour and I’ll be discussing approaches to timing cancer immunotherapy. See you there!
June 9, 2025 at 9:14 PM
Reposted by Selma Masri
birdlady.bsky.social
race does not equal genes
www.statnews.com/2025/06/05/n...
Massive NIH study challenges use of race as a proxy for genetic ancestry in research
A large government study shows that Americans’ self-reported race is a poor proxy for their genetic ancestry.
www.statnews.com
June 6, 2025 at 12:38 AM
Reposted by Selma Masri
jenniferhurleylab.bsky.social
Thanks to @npr.org and the Shortwave podcast for covering circadian research! It was very cool to be on the podcast and on All Things Considered. And Kudos to Chris Hall for the exciting work.

www.npr.org/2025/05/29/n...

www.npr.org/2025/05/30/1...
This week in science: hawks hunting, infrared contacts and immunity through the day
Berly McCoy and Regina Barber of Short Wave talk about a hawk's clever hunting strategy, contacts that allow wearers to see infrared light, and how immunity varies during the day.
www.npr.org
May 30, 2025 at 12:43 PM
Reposted by Selma Masri
pannunziolab.bsky.social
Check out our latest story @natcancer.nature.com co-led with @masrilab.bsky.social that reviews how the circadian clock intersects several aspects of cancer biology. Excited to be part of this collaborative team effort to understand impacts on DNA repair, early onset cancer, and cancer treatment 💪🧬🕔
May 28, 2025 at 3:25 PM
masrilab.bsky.social
Super happy to share our latest in @natcancer.nature.com co-led by @pannunziolab.bsky.social! We review the complex role of the circadian clock in genome integrity, DNA repair, immunity, metabolism, and cancer with a specific focus on early-onset cancer. Check it out!

www.nature.com/articles/s43...
The diverse roles of the circadian clock in cancer - Nature Cancer
Masri and colleagues review the latest studies on the influence of circadian rhythms in cancer biology, discussing possible connections between chronobiology and cancer prevention and treatment.
www.nature.com
May 27, 2025 at 4:56 PM
Reposted by Selma Masri
talliezee.bsky.social
Celebrating UCI school of medicine graduate students 🧪🧠 . You are the future of #science @ucirvine.bsky.social @cnlm.bsky.social @neurohoke.bsky.social
May 16, 2025 at 8:04 PM
Reposted by Selma Masri
needhibhalla.bsky.social
I just emailed my state representatives to support Newsom's new budget for UC. If you agree that this economic and social engine for California needs robust state support, please join me.

universityofcalifornia.quorum.us/campaign/sta...
Time for Action!
Urge legislators to fund UC!
universityofcalifornia.quorum.us
May 15, 2025 at 6:01 PM
Reposted by Selma Masri
claudiocantu81.bsky.social
We had previously shown that TBX3 and #WNT cooperate in limb #DevBio

We now have a shocking finding, just published in @pnas.org

TBX3 physically engages with β-catenin to drive metastasis genes in #ColorectalCancer (CRC)

www.pnas.org/doi/epub/10....
The developmental factor TBX3 engages with the Wnt/β-catenin transcriptional complex in colorectal cancer to regulate metastasis genes
www.pnas.org
May 12, 2025 at 7:33 AM
Reposted by Selma Masri
ppagella86.bsky.social
Fresh out of press: our new chapter on the TBX3/WNT liaison, and how it drives metastasis-related genes expression in colorectal cancer, out on @pnas.org

Enjoy the “bluetorial” by @claudiocantu81.bsky.social below! 👇🏼

#WNT #CRC @liu.se

www.pnas.org/doi/10.1073/...
May 13, 2025 at 5:59 AM
Reposted by Selma Masri
cosimocommisso.bsky.social
New preprint! 🧓⚡️ Aging drives immune exclusion & metastasis in PDAC by rewiring the tumor stroma. Young CAFs ♻️ rejuvenate the aged microenvironment & restore immune infiltration.
Read: www.biorxiv.org/content/10.1...

#PDAC #Aging #TumorMicroenvironment #Preprint
The Aging Microenvironment as a Determinant of Immune Exclusion and Metastatic Fate in Pancreatic Cancer
Aging is a critical yet understudied determinant in pancreatic ductal adenocarcinoma (PDAC). Despite a strong epidemiological association with age, conventional PDAC preclinical models fail to capture...
www.biorxiv.org
May 11, 2025 at 3:11 PM
masrilab.bsky.social
Just watched this episode. John Oliver did an outstanding job breaking everything down, even what indirects costs are! It’s our job to get all this information out, especially to inform the general public. This needs to stop. Now.
jeremymberg.bsky.social Jeremy Berg @jeremymberg.bsky.social · Apr 28
Here is the link to the Last Week Tonight with John Oliver about RFK, Jr, public health, and HHS (including NIH)

www.youtube.com/watch?v=8H34...
RFK Jr. & HHS: Last Week Tonight with John Oliver (HBO)
YouTube video by LastWeekTonight
www.youtube.com
April 29, 2025 at 1:53 PM
Reposted by Selma Masri
jeremymberg.bsky.social
Sunday TV viewing...More to come later

Lead story about NIH...

www.paramountpressexpress.com/cbs-news-and...
Paramount Press Express | “60 MINUTES” LISTINGS FOR SUNDAY, APRIL 27
Airs 7:00-8:00 PM, ET/ PT on the CBS Television Network NIH – In its ongoing mission to shrink the federal government, the Trump administration has cut
www.paramountpressexpress.com
April 25, 2025 at 1:26 PM
Reposted by Selma Masri
science.org
President Donald Trump’s administration appears to be killing much, if not all, of a historic initiative that was the first, and is still the largest, National Institutes of Health effort centered on the health needs of women. scim.ag/4jLeLTJ
NIH cancels its first and largest study centered on women
The Women’s Health Initiative has produced numerous influential findings
scim.ag
April 23, 2025 at 1:44 PM
Reposted by Selma Masri
ashi-w.bsky.social
This breaks my heart in ways I can’t quite describe.
drmlb.bsky.social Mary Brandt, MD, MDiv @drmlb.bsky.social · Apr 22
"We are close to 300 [worshipers] but nowadays we are only less than 150. People are sick at home," says Chondwe — or Pastor Billy as everyone calls him... People are falling ill because the U.S.-funded clinics where they got their HIV medications and care have suddenly been shuttered.
Haunted by hopelessness: 12 Zambians share their stories as HIV drugs run out
Mothers and children, husbands and wives, doctors, truck drivers and religious leaders are all grappling with the fallout from the sudden U.S. cuts in aid.
www.npr.org
April 22, 2025 at 1:39 PM
Reposted by Selma Masri
jeremymberg.bsky.social
New STAT story about the possible new NIH grants terms and conditions

www.statnews.com/2025/04/21/t...
NIH moving to ban all future grants to universities with DEI programs or Israel boycotts, document suggests
NIH appears to be preparing to prohibit the awarding of new grants to institutions that have DEI programs or boycott Israeli companies
www.statnews.com
April 21, 2025 at 4:33 PM
Reposted by Selma Masri
joanna-chiu.bsky.social
www.ucdavis.edu/research/lab...
@ucdavis.bsky.social
@ucdavishealth.bsky.social
@ucdavisplants.bsky.social
@ucdaviscns.bsky.social
@ucdavispsych.bsky.social
From Labs to Lives
UC Davis researchers describe the impact of their work and the life-altering consequences if federal funding for medical research were reduced or eliminated.
www.ucdavis.edu
April 19, 2025 at 4:51 PM
Reposted by Selma Masri
jeremymberg.bsky.social
STAT story about freezing all payments to Columbia, Harvard, Brown, Northwestern, Cornell, and Cornell-Weill Medicine.

www.statnews.com/2025/04/18/n...
NIH said to have halted awarding of new grants to top universities
Universities whose NIH funding has been frozen may face further strain as the agency holds off awarding new grants to at least a half dozen of them, according to an internal email.
www.statnews.com
April 18, 2025 at 11:08 PM
Reposted by Selma Masri
npr.org
A presidential effort to revoke Harvard University's tax-exempt status could run up against a number of challenges, including violating federal law.
History shows revoking Harvard's tax status won't be easy — or fast
A presidential effort to revoke Harvard University's tax-exempt status could run up against a number of challenges, including violating federal law.
www.npr.org
April 18, 2025 at 8:47 PM
Reposted by Selma Masri
pannunziolab.bsky.social
The cast and crew of Pannunzio Lab season 6! Despite everything going on we continue to grow and be productive. Their excitement about science is contagious. These are the people that keep me coming in every day 💪🫀🧬
April 19, 2025 at 1:01 AM