Adele Marston
@marstonlab.bsky.social
Cell Biologist excited about Chromosomes, Meiosis and Mitosis. Director, Wellcome Discovery Platform for Hidden Cell Biology
A special thanks to the fly expert reviewers for helping us clarify a few points, including the late Scott Hawley, whose review was filled with the enthusiasm and generosity we all knew him for.
February 26, 2025 at 9:50 PM
A special thanks to the fly expert reviewers for helping us clarify a few points, including the late Scott Hawley, whose review was filled with the enthusiasm and generosity we all knew him for.
I am very shocked and saddened to hear this news. He made so many important contributions in so many different ways.
January 31, 2025 at 7:45 PM
I am very shocked and saddened to hear this news. He made so many important contributions in so many different ways.
See also related work by @eecutts.bsky.social and thanks to Erin and Luis for a great co-submission experience www.embopress.org/doi/full/10....
Molecular mechanism of condensin I activation by KIF4A | The EMBO Journal
imageimageHow loss of KIF4A chromokinesin reduces chromosome association of condensin has remained
unclear. This study demonstrates that human condensin I is auto-inhibited by short
linear motifs (SLi...
www.embopress.org
December 18, 2024 at 10:06 AM
See also related work by @eecutts.bsky.social and thanks to Erin and Luis for a great co-submission experience www.embopress.org/doi/full/10....
Overall we show that Mad3 acts outside of its checkpoint role to actively direct chromosome segregation.
January 6, 2024 at 9:10 AM
Overall we show that Mad3 acts outside of its checkpoint role to actively direct chromosome segregation.
We found that Mad3 binds the Stu1 (CLASP) microtubule regulator through its degenerate TOGL1 domain. We showed that Mad3-Stu1 association rescues the segregation of chromosomes that lack crossovers or fail to biorient in meiosis I.
January 6, 2024 at 9:09 AM
We found that Mad3 binds the Stu1 (CLASP) microtubule regulator through its degenerate TOGL1 domain. We showed that Mad3-Stu1 association rescues the segregation of chromosomes that lack crossovers or fail to biorient in meiosis I.
We discovered that in addition to its well known role in delaying the cell cycle as part of the spindle checkpoint, Mad3, has a separate role in promoting chromosome alignment on the spindle in budding yeast meiosis.
January 6, 2024 at 9:09 AM
We discovered that in addition to its well known role in delaying the cell cycle as part of the spindle checkpoint, Mad3, has a separate role in promoting chromosome alignment on the spindle in budding yeast meiosis.