markus
markusjsommer.bsky.social
markus
@markusjsommer.bsky.social
PI, Bioinformatics, NBACC

Previously: Johns Hopkins Center for Computational Biology
Reposted by markus
Out now in @genomebiolevol.bsky.social! With colleagues at NBACC and PNNL, we helped answer a long-standing question about how widely-divergent cyanobacteria produce saxitoxin, a major cause of paralytic shellfish poisoning. We assembled a new genome for a producer of saxitoxin and ...
Novel Toxin Biosynthetic Gene Cluster in Harmful Algal Bloom-Causing Heteroscytonema crispum: Insights into the Origins of Paralytic Shellfish Toxins
Abstract. Caused by both eukaryotic dinoflagellates and prokaryotic cyanobacteria, harmful algal blooms are events of severe ecological, economic, and publ
academic.oup.com
January 14, 2025 at 3:07 AM
Reposted by markus
Check out our just-published AI-based (temporal convolutional network) system, PSAURON, for predicting eukaryotic proteins, from @markusjsommer.bsky.social. We used a similar method in BALROG, our bacterial gene finder. Note: the "P" is silent in PSAURON 🤣 academic.oup.com/nargab/artic...
PSAURON: a tool for assessing protein annotation across a broad range of species
Abstract. Evaluating the accuracy of protein-coding sequences in genome annotations is a challenging problem for which there is no broadly applicable solut
academic.oup.com
January 11, 2025 at 6:22 PM