Cyclist.
https://hyvonen.bioc.cam.ac.uk
All of three 🤷🏻♂️
All of three 🤷🏻♂️
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We started with mM affinity fragments, ended up with a low nM inhibitor CAM2602 (see below, PDB: 8C1K)
doi.org/10.1021/acs....
#FBDD #Kinase #medchem
We started with mM affinity fragments, ended up with a low nM inhibitor CAM2602 (see below, PDB: 8C1K)
doi.org/10.1021/acs....
#FBDD #Kinase #medchem