Mark Gresnigt
@markgresnigt.bsky.social
Junior group leader of @aps-hki.bsky.social at the Leibniz-HKI in Jena, interested in protective immunity against fungal infections and fungal immune evasion.
🇳🇱 in 🇩🇪, cycling 🚴🏼♂️ addicted.
🇳🇱 in 🇩🇪, cycling 🚴🏼♂️ addicted.
Reposted by Mark Gresnigt
My group at is hiring a PhD student to explore how fungal pathogens that live in the environment will adapt their genomes, acquire new phenotypes, and perhaps even increased infectivity as a result of climate change. Please share!
More info and applications at @ jobs.uni-jena.de/vrbup
More info and applications at @ jobs.uni-jena.de/vrbup
July 29, 2025 at 3:41 PM
My group at is hiring a PhD student to explore how fungal pathogens that live in the environment will adapt their genomes, acquire new phenotypes, and perhaps even increased infectivity as a result of climate change. Please share!
More info and applications at @ jobs.uni-jena.de/vrbup
More info and applications at @ jobs.uni-jena.de/vrbup
Reposted by Mark Gresnigt
💡 New infection strategy in #Candida albicans discovered: human #albumin reprograms its metabolism, turning harmless strains pathogenic – without the need of hyphae or toxins. #LeibnizHKI
🗞️ lmy.de/mthFi
🧪 rdcu.be/exl7d
@markgresnigt.bsky.social @aps-hki.bsky.social
@dfg.de @microverse.bsky.social
🗞️ lmy.de/mthFi
🧪 rdcu.be/exl7d
@markgresnigt.bsky.social @aps-hki.bsky.social
@dfg.de @microverse.bsky.social
July 22, 2025 at 3:30 PM
💡 New infection strategy in #Candida albicans discovered: human #albumin reprograms its metabolism, turning harmless strains pathogenic – without the need of hyphae or toxins. #LeibnizHKI
🗞️ lmy.de/mthFi
🧪 rdcu.be/exl7d
@markgresnigt.bsky.social @aps-hki.bsky.social
@dfg.de @microverse.bsky.social
🗞️ lmy.de/mthFi
🧪 rdcu.be/exl7d
@markgresnigt.bsky.social @aps-hki.bsky.social
@dfg.de @microverse.bsky.social
Reposted by Mark Gresnigt
We are exited to share our story just out in @natcomms.nature.com on how the yeast Candida albicans can exploit human albumin to engage an alternative pathogenicity pathway, not relying on previously uncovered virulence factors.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Host albumin redirects Candida albicans metabolism to engage an alternative pathogenicity pathway - Nature Communications
Candida albicans normally relies on specific pathogenicity mechanisms to cause tissue damage. This study reveals that when sensing host albumin, C. albicans, even avirulent strains, can trigger an alt...
www.nature.com
July 14, 2025 at 2:51 PM
We are exited to share our story just out in @natcomms.nature.com on how the yeast Candida albicans can exploit human albumin to engage an alternative pathogenicity pathway, not relying on previously uncovered virulence factors.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Mark Gresnigt
Our newest review is published in @femsjournals.bsky.social! Marisa Valentine discusses the host-pathogen-microbiome interactions during #vaginal #Candida infections.🍄🧫🦠
Big thank you to Duncan Wilson and @markgresnigt.bsky.social for contributing!
👉 academic.oup.com/femsre/advan...
Big thank you to Duncan Wilson and @markgresnigt.bsky.social for contributing!
👉 academic.oup.com/femsre/advan...
May 12, 2025 at 1:12 PM
Our newest review is published in @femsjournals.bsky.social! Marisa Valentine discusses the host-pathogen-microbiome interactions during #vaginal #Candida infections.🍄🧫🦠
Big thank you to Duncan Wilson and @markgresnigt.bsky.social for contributing!
👉 academic.oup.com/femsre/advan...
Big thank you to Duncan Wilson and @markgresnigt.bsky.social for contributing!
👉 academic.oup.com/femsre/advan...
Reposted by Mark Gresnigt
What an incredible joint meeting „FungiNet – Pathogenic fungiand their human host“ & „Invasive Mycoses in Haematological Malignancies – IMIHM XV in Würzburg!
🌟 The discussions were enlightening, and the talks were truly inspiring.
🙌 A big thank you to everyone involved!
🌟 The discussions were enlightening, and the talks were truly inspiring.
🙌 A big thank you to everyone involved!
March 31, 2025 at 5:31 PM
What an incredible joint meeting „FungiNet – Pathogenic fungiand their human host“ & „Invasive Mycoses in Haematological Malignancies – IMIHM XV in Würzburg!
🌟 The discussions were enlightening, and the talks were truly inspiring.
🙌 A big thank you to everyone involved!
🌟 The discussions were enlightening, and the talks were truly inspiring.
🙌 A big thank you to everyone involved!
Reposted by Mark Gresnigt
The meeting ended with an exciting panel discussion on possible future directions after 12 glorious years of the @dfg.de funded @trr124-funginet.bsky.social consortium. With @estukenbrock.bsky.social, Oliver Kurzai, Axel Brakhage and others.
April 1, 2025 at 1:04 PM
The meeting ended with an exciting panel discussion on possible future directions after 12 glorious years of the @dfg.de funded @trr124-funginet.bsky.social consortium. With @estukenbrock.bsky.social, Oliver Kurzai, Axel Brakhage and others.
Reposted by Mark Gresnigt
Cracks in the Curriculum: The Hidden Deficiencies in Fungal Disease Coverage in Medical Books
Isabela Rost / Alessandro Pasqualotto and colleagues
academic.oup.com/ofid/article...
Isabela Rost / Alessandro Pasqualotto and colleagues
academic.oup.com/ofid/article...
Cracks in the Curriculum: The Hidden Deficiencies in Fungal Disease Coverage in Medical Books
Abstract. Textbooks remain a primary source of reference and education for many health care professionals and students. This study assessed the mycology co
academic.oup.com
April 1, 2025 at 3:57 PM
Cracks in the Curriculum: The Hidden Deficiencies in Fungal Disease Coverage in Medical Books
Isabela Rost / Alessandro Pasqualotto and colleagues
academic.oup.com/ofid/article...
Isabela Rost / Alessandro Pasqualotto and colleagues
academic.oup.com/ofid/article...
Reposted by Mark Gresnigt
Fascinating evening🌇keynote given by David @sancholab.bsky.social on how the gut microbiome trains the immune system inside the bone marrow🦴 and how its metabolites impact atherosclerosis 👏🏻
March 25, 2025 at 10:22 AM
Fascinating evening🌇keynote given by David @sancholab.bsky.social on how the gut microbiome trains the immune system inside the bone marrow🦴 and how its metabolites impact atherosclerosis 👏🏻
Reposted by Mark Gresnigt
And keynote speaker of day 2 Karsten Hiller of @tubraunschweig.bsky.social is giving us a deep dive into immuno metabolism in macrophages: #itaconate rules ✌🏻🤓 #Rothenfels2025
March 25, 2025 at 9:31 PM
And keynote speaker of day 2 Karsten Hiller of @tubraunschweig.bsky.social is giving us a deep dive into immuno metabolism in macrophages: #itaconate rules ✌🏻🤓 #Rothenfels2025
Reposted by Mark Gresnigt
We are incredibly proud of Kar On Cheng for winning the best presentation award at the 28th Symposium: "Infection and Immune Defense". She presented her doctorate project on IL-36 and its role in inflammation during RVVC. Congratulations Kar On!!!
March 26, 2025 at 12:26 PM
We are incredibly proud of Kar On Cheng for winning the best presentation award at the 28th Symposium: "Infection and Immune Defense". She presented her doctorate project on IL-36 and its role in inflammation during RVVC. Congratulations Kar On!!!
My group @aps-hki.bsky.social is looking for a new postdoc in immunology of fungal infections focusing on vulvovaginal candidiasis. Please contact me for further details in case of interest.
March 19, 2025 at 5:55 PM
My group @aps-hki.bsky.social is looking for a new postdoc in immunology of fungal infections focusing on vulvovaginal candidiasis. Please contact me for further details in case of interest.
Reposted by Mark Gresnigt
Reposted by Mark Gresnigt
Pathogenic microorganisms employ adaptive strategies to escape host defense. Hitzler et al. explore how bacterial and fungal pathogens escape the host immune system. https://buff.ly/4ajQ9On
#FEMSMicrobiolRev
@markgresnigt.bsky.social
#FEMSMicrobiolRev
@markgresnigt.bsky.social
January 16, 2025 at 9:00 AM
Pathogenic microorganisms employ adaptive strategies to escape host defense. Hitzler et al. explore how bacterial and fungal pathogens escape the host immune system. https://buff.ly/4ajQ9On
#FEMSMicrobiolRev
@markgresnigt.bsky.social
#FEMSMicrobiolRev
@markgresnigt.bsky.social
Proud to share our latest article with the group of Mihai Netea showing that lactic acid in the vaginal milieu modulates the Candida-host interactions that underlie the immune responses associated with vulvovaginal candidiasis www.tandfonline.com/doi/full/10....
Lactic acid in the vaginal milieu modulates the Candida-host interaction
Vulvovaginal candidiasis (VVC) is one of the most common infections caused by Candida albicans. VVC is characterized by an inadequate hyperinflammatory response and clinical symptoms associated wit...
www.tandfonline.com
January 23, 2025 at 5:32 AM
Proud to share our latest article with the group of Mihai Netea showing that lactic acid in the vaginal milieu modulates the Candida-host interactions that underlie the immune responses associated with vulvovaginal candidiasis www.tandfonline.com/doi/full/10....
Reposted by Mark Gresnigt
Join our team at the Leibniz-HKI as Technical Assistant - application deadline closing soon! 📣
Job alert! We have an open technician position in our lab at the Leibniz-HKI, please spread the word!
jobs.hki-jena.de/jobs/Technis...
jobs.hki-jena.de/jobs/Technis...
Stellenangebot Technische*r Assistent*in (m/w/div) oder Biologielaborant*in bei Leibniz HKI Jobportal
Wissenschaft/Forschung in Jena
jobs.hki-jena.de
January 6, 2025 at 3:02 PM
Join our team at the Leibniz-HKI as Technical Assistant - application deadline closing soon! 📣
Reposted by Mark Gresnigt
We are excited to share that in the last few days of 2024 our review on how bacterial and fungal pathogens🦠🍄🧫 bind and/or sense immune mediators to evade and escape the immune system has been published in @femsjournals.bsky.social #FEMSMicrobiologyReviews.
academic.oup.com/femsre/advan...
academic.oup.com/femsre/advan...
Microbial adaptive pathogenicity strategies to the host inflammatory environment
Abstract. Pathogenic microorganisms can infect a variety of niches in the human body. During infection, microbes can only persist if they adapt adequately
academic.oup.com
January 2, 2025 at 10:39 AM
We are excited to share that in the last few days of 2024 our review on how bacterial and fungal pathogens🦠🍄🧫 bind and/or sense immune mediators to evade and escape the immune system has been published in @femsjournals.bsky.social #FEMSMicrobiologyReviews.
academic.oup.com/femsre/advan...
academic.oup.com/femsre/advan...
Reposted by Mark Gresnigt
In the past years, I've found using comic-inspired color palettes super helpful when creating figures for my papers. Just came across this one and I’m definitely using it next!
💡Any comic recommendations with cool color palettes?🌈
#AcademicSky @academic-chatter.bsky.social @thephdplace.bsky.social
💡Any comic recommendations with cool color palettes?🌈
#AcademicSky @academic-chatter.bsky.social @thephdplace.bsky.social
November 24, 2024 at 7:29 PM
In the past years, I've found using comic-inspired color palettes super helpful when creating figures for my papers. Just came across this one and I’m definitely using it next!
💡Any comic recommendations with cool color palettes?🌈
#AcademicSky @academic-chatter.bsky.social @thephdplace.bsky.social
💡Any comic recommendations with cool color palettes?🌈
#AcademicSky @academic-chatter.bsky.social @thephdplace.bsky.social
Shocking moment today: Got told by the pediatrician today that I should open a bottle of prosecco to celebrate that our son was now through his full first set of vaccinations. Apparently is not that common anymore that people let their children be fully vaccinated 🤯
November 22, 2024 at 9:43 AM
Shocking moment today: Got told by the pediatrician today that I should open a bottle of prosecco to celebrate that our son was now through his full first set of vaccinations. Apparently is not that common anymore that people let their children be fully vaccinated 🤯
Reposted by Mark Gresnigt
In our @dfgpublic.bsky.social funded research grouop we use this system in our lab to see how Candida albicans adapts to the different host stimuli we expose it to.
November 14, 2024 at 9:53 AM
In our @dfgpublic.bsky.social funded research grouop we use this system in our lab to see how Candida albicans adapts to the different host stimuli we expose it to.
Reposted by Mark Gresnigt
For our first post, we would like to share that we are enjoying how our live-cell imaging system (Funded by the state of Thuringia and co-funded by the EU) can use a neuron tool to quantify fungal hyphal growth.
See the paper by Wurster et al. who established this journals.asm.org/doi/epub/10....
See the paper by Wurster et al. who established this journals.asm.org/doi/epub/10....
November 14, 2024 at 9:53 AM
For our first post, we would like to share that we are enjoying how our live-cell imaging system (Funded by the state of Thuringia and co-funded by the EU) can use a neuron tool to quantify fungal hyphal growth.
See the paper by Wurster et al. who established this journals.asm.org/doi/epub/10....
See the paper by Wurster et al. who established this journals.asm.org/doi/epub/10....
This week my group started to work in our new labspace at the Leibniz-HKI after a lot of restructuring and reorganization. Happy we can finally get some experiments done in the new rooms.
November 19, 2023 at 5:55 PM
This week my group started to work in our new labspace at the Leibniz-HKI after a lot of restructuring and reorganization. Happy we can finally get some experiments done in the new rooms.
Hello 👋🏼 all. Happy to join here for the science chats
October 10, 2023 at 7:20 PM
Hello 👋🏼 all. Happy to join here for the science chats