marjonverstegen.bsky.social
@marjonverstegen.bsky.social
Reposted
On 🌎World Sickle Cell Day🩸 we share a new gene therapy approach that holds promise for patients with sickle cell disease, thalassemia and possibly other genetic diseases.🧬 Researchers from the Hubrecht Institute, Erasmus MC, Sanquin and Oncode found a new method to switch genes on.
June 19, 2025 at 12:34 PM
Reposted
What do long-range enhancers need to regulate genes? Researchers from the De Laat group have found that long-range enhancers require optimal regulatory protein levels, in addition to the specific protein complex cohesin, to switch on genes.

Read more here: www.hubrecht.eu/long-range-e...
Long-range enhancers more sensitive to regulatory proteins than short-range enhancers
Genes regulated by long-range enhancers are more sensitive to disturbances of regulatory protein levels than those regulated by short-range enhancers.
www.hubrecht.eu
February 25, 2025 at 4:20 PM