Marino Pagan
@marinopagan.bsky.social
Group Leader at SIDB at the University of Edinburgh studying the neural mechanisms underlying flexible decision-making. SCGB postdoctoral fellow and SFARI BTI fellow. (he/him) https://www.marinopagan.com/pagan_lab/
Pinned
Marino Pagan
@marinopagan.bsky.social
· Mar 21
Individual variability of neural computations underlying flexible decisions - Nature
Behavioural experiments to study decision-making in response to context-dependent accumulation of evidence provide testable models that are consistent with the heterogeneity in neural signatures among...
www.nature.com
1/7 Our paper on individual variability in decision-making is finally out in @nature.com! Inspired by the classic work by Mante and Sussillo, we trained many rats to solve context-dependent decision-making, and we found that different brains use different neural mechanisms to solve the same task!
My small tribute to one of my favourite papers ever
In our latest edition of “This paper changed my life,” @marinopagan.bsky.social reflects on a seminal paper that revealed the complexity of neural population dynamics and the power of recurrent neural networks.
#neuroskyence
www.thetransmitter.org/this-paper-c...
#neuroskyence
www.thetransmitter.org/this-paper-c...
Seminal study on the neural mechanisms of decision-making
Valerio Mante and David Sussillo’s study showed neuroscience the power of recurrent neural networks.
www.thetransmitter.org
May 19, 2025 at 8:03 AM
My small tribute to one of my favourite papers ever
Reposted by Marino Pagan
we're crowd-sourcing a searchable repository of tangible benefits stemming from federally-funded research. Come enjoy the great stories; or send in an idea; or volunteer to join the team.
publicusaresearchbenefits.com
please share and re-share so we get more great stories in there!
publicusaresearchbenefits.com
please share and re-share so we get more great stories in there!
Searchable database of tangible benefits that federally-funded research gave us.
A crowd-sourced site. Health and Well-being. National Security. Prosperity.
publicusaresearchbenefits.com
May 7, 2025 at 11:28 PM
we're crowd-sourcing a searchable repository of tangible benefits stemming from federally-funded research. Come enjoy the great stories; or send in an idea; or volunteer to join the team.
publicusaresearchbenefits.com
please share and re-share so we get more great stories in there!
publicusaresearchbenefits.com
please share and re-share so we get more great stories in there!
🚨 Deadline extended! 🚨
A few more days to apply for this PhD project in my lab - come to Edinburgh and study flexible decision-making with us!
Please share if you know someone who might be interested 🙂
A few more days to apply for this PhD project in my lab - come to Edinburgh and study flexible decision-making with us!
Please share if you know someone who might be interested 🙂
Deadline of this PhD application has been extended to 10 APRIL! Find out more and apply here
April 7, 2025 at 9:04 AM
🚨 Deadline extended! 🚨
A few more days to apply for this PhD project in my lab - come to Edinburgh and study flexible decision-making with us!
Please share if you know someone who might be interested 🙂
A few more days to apply for this PhD project in my lab - come to Edinburgh and study flexible decision-making with us!
Please share if you know someone who might be interested 🙂
We are hiring a PhD student to study the neural mechanisms underlying flexible decision-making and individual variability. Please apply and spread the word!
The Pagan lab is advertising for a 3.5 year fully funded PhD studentship to start in 2025 within SIDB at Edinburgh University, investigating the neural mechanism underlying flexible decision-making.
🗓️Deadline: 4 April 2024
👇Find out more and apply now:
sidb.org.uk/phds/study-o...
🗓️Deadline: 4 April 2024
👇Find out more and apply now:
sidb.org.uk/phds/study-o...
March 28, 2025 at 1:46 PM
We are hiring a PhD student to study the neural mechanisms underlying flexible decision-making and individual variability. Please apply and spread the word!
I am hiring a PhD student in my lab in beautiful Edinburgh to keep investigating the neural mechanisms underlying flexible decision-making and individual variability.
Email or DM me with any questions, or let's chat at the CoSyNe Main Meeting next week!
Apply here: tinyurl.com/2cxr6nbg
Email or DM me with any questions, or let's chat at the CoSyNe Main Meeting next week!
Apply here: tinyurl.com/2cxr6nbg
March 24, 2025 at 7:55 PM
I am hiring a PhD student in my lab in beautiful Edinburgh to keep investigating the neural mechanisms underlying flexible decision-making and individual variability.
Email or DM me with any questions, or let's chat at the CoSyNe Main Meeting next week!
Apply here: tinyurl.com/2cxr6nbg
Email or DM me with any questions, or let's chat at the CoSyNe Main Meeting next week!
Apply here: tinyurl.com/2cxr6nbg
1/7 Our paper on individual variability in decision-making is finally out in @nature.com! Inspired by the classic work by Mante and Sussillo, we trained many rats to solve context-dependent decision-making, and we found that different brains use different neural mechanisms to solve the same task!
Individual variability of neural computations underlying flexible decisions - Nature
Behavioural experiments to study decision-making in response to context-dependent accumulation of evidence provide testable models that are consistent with the heterogeneity in neural signatures among...
www.nature.com
March 21, 2025 at 1:29 PM
1/7 Our paper on individual variability in decision-making is finally out in @nature.com! Inspired by the classic work by Mante and Sussillo, we trained many rats to solve context-dependent decision-making, and we found that different brains use different neural mechanisms to solve the same task!
Reposted by Marino Pagan
A surprising variability in how rats process sounds, evaluate evidence, and make choices underscores the complexity of the brain’s decision-making process, finds a new study in @nature.com from the labs of PNI's Carlos Brody and @jpillowtime.bsky.social. pni.princeton.edu/news/2025/ne...
A new “hearing test” for rats reveals the brain’s hidden variability when making a decision
Simple choices can arise from diverse brain strategies, shedding light on the origins of individual variability
pni.princeton.edu
January 21, 2025 at 3:20 PM
A surprising variability in how rats process sounds, evaluate evidence, and make choices underscores the complexity of the brain’s decision-making process, finds a new study in @nature.com from the labs of PNI's Carlos Brody and @jpillowtime.bsky.social. pni.princeton.edu/news/2025/ne...
Reposted by Marino Pagan
We are pleased to be partnering with The UKRI AI CDT in Biomedical Innovation at the School of Informatics (University of Edinburgh). These PhD projects have a strong translational focus and seek to develop & apply AI approaches to biomedical domains ✨.
Apply by 20 Jan www.ai4biomed.io/how-to-apply/
Apply by 20 Jan www.ai4biomed.io/how-to-apply/
January 16, 2025 at 10:53 AM
We are pleased to be partnering with The UKRI AI CDT in Biomedical Innovation at the School of Informatics (University of Edinburgh). These PhD projects have a strong translational focus and seek to develop & apply AI approaches to biomedical domains ✨.
Apply by 20 Jan www.ai4biomed.io/how-to-apply/
Apply by 20 Jan www.ai4biomed.io/how-to-apply/
Reposted by Marino Pagan
Thanks to our recent Wellcome funding- we're hiring a Postdoctoral Researcher to explore the mechanisms underlying synaptic RNA capture and selective local protein synthesis. This position has 5 years of funding. Please reach out if you have any questions!
elxw.fa.em3.oraclecloud.com/hcmUI/Candid...
elxw.fa.em3.oraclecloud.com/hcmUI/Candid...
Postdoctoral Research Fellow
We seek a motivated postdoctoral researcher to conduct primary research into how neurons transport mRNA to distal sites and use these mRNAs as substrates for local protein synthesis during synaptic pl...
elxw.fa.em3.oraclecloud.com
January 9, 2025 at 2:54 PM
Thanks to our recent Wellcome funding- we're hiring a Postdoctoral Researcher to explore the mechanisms underlying synaptic RNA capture and selective local protein synthesis. This position has 5 years of funding. Please reach out if you have any questions!
elxw.fa.em3.oraclecloud.com/hcmUI/Candid...
elxw.fa.em3.oraclecloud.com/hcmUI/Candid...
Reposted by Marino Pagan
There’s just under 2 weeks to apply for our PhD studentships! Join our dynamic community where we provide an annual stipend of £25K, plus tuition fees (inc. international) 🧠.
Apply by 26 January and start your journey with us: sidb.org.uk/phds/
@edinburghmedschool.bsky.social
Apply by 26 January and start your journey with us: sidb.org.uk/phds/
@edinburghmedschool.bsky.social
January 14, 2025 at 12:38 PM
There’s just under 2 weeks to apply for our PhD studentships! Join our dynamic community where we provide an annual stipend of £25K, plus tuition fees (inc. international) 🧠.
Apply by 26 January and start your journey with us: sidb.org.uk/phds/
@edinburghmedschool.bsky.social
Apply by 26 January and start your journey with us: sidb.org.uk/phds/
@edinburghmedschool.bsky.social
I think Marr levels are a great framework to study mental disorders:1) what computations are altered? 2) What neural mechanisms (at Systems level) cause these altered computations? 3) What are the underlying cellular/molecular changes? We know a lot about 3), little about 1), almost nothing about 2)
A few weeks ago Sebastian Seung (are you here yet?) posted
"Marr's three levels are dead. AI killed them."
and a fun discussion ensued.
But although many of us grew up with the 3 levels, it was not clear to me that anyone actually still believes in and defends them?
Is this still debated?
"Marr's three levels are dead. AI killed them."
and a fun discussion ensued.
But although many of us grew up with the 3 levels, it was not clear to me that anyone actually still believes in and defends them?
Is this still debated?
December 1, 2024 at 2:37 PM
I think Marr levels are a great framework to study mental disorders:1) what computations are altered? 2) What neural mechanisms (at Systems level) cause these altered computations? 3) What are the underlying cellular/molecular changes? We know a lot about 3), little about 1), almost nothing about 2)
Reposted by Marino Pagan
SIDB has partnered with The UKRI AI CDT in Biomedical Innovation. Our PhD studentships have a strong translational focus and seek to develop & apply AI approaches to biomedical domains.
Find out more & apply by 20th Jan >> www.ai4biomed.io/research/pro...
@tisimpson.bsky.social
Find out more & apply by 20th Jan >> www.ai4biomed.io/research/pro...
@tisimpson.bsky.social
November 20, 2024 at 2:03 PM
SIDB has partnered with The UKRI AI CDT in Biomedical Innovation. Our PhD studentships have a strong translational focus and seek to develop & apply AI approaches to biomedical domains.
Find out more & apply by 20th Jan >> www.ai4biomed.io/research/pro...
@tisimpson.bsky.social
Find out more & apply by 20th Jan >> www.ai4biomed.io/research/pro...
@tisimpson.bsky.social
🚨 PhD opportunity alert! 🚨
Join our lab @sidb-edinburgh.bsky.social in beautiful Edinburgh! We study the neural mechanisms underlying flexible decision-making using cutting-edge experimental and computational approaches.
We’re recruiting for two fully funded PhD positions. Details below 👇
Join our lab @sidb-edinburgh.bsky.social in beautiful Edinburgh! We study the neural mechanisms underlying flexible decision-making using cutting-edge experimental and computational approaches.
We’re recruiting for two fully funded PhD positions. Details below 👇
November 24, 2024 at 10:52 AM
🚨 PhD opportunity alert! 🚨
Join our lab @sidb-edinburgh.bsky.social in beautiful Edinburgh! We study the neural mechanisms underlying flexible decision-making using cutting-edge experimental and computational approaches.
We’re recruiting for two fully funded PhD positions. Details below 👇
Join our lab @sidb-edinburgh.bsky.social in beautiful Edinburgh! We study the neural mechanisms underlying flexible decision-making using cutting-edge experimental and computational approaches.
We’re recruiting for two fully funded PhD positions. Details below 👇