mariajsasilva.bsky.social
@mariajsasilva.bsky.social
Postdoc|@WeilTanja|@mpi_polymer
Alumni|@GoisLab|@iMedULisboa|@ULisboa_ and @GasserGroup|@ChimieParisTech|@psl_univ
Reposted
Excited to share our latest research published in @natcomms.nature.com, where we explore a 1,6-addition of thiols to N-alkylpyridinium for site-selective dual modification of proteins. Congratulations to the team!
👉 www.nature.com/articles/s41...
#Bioconjugation
@seahling.bsky.social
Chemoselective dual functionalization of proteins via 1,6-addition of thiols to trifunctional N-alkylpyridinium - Nature Communications
Chemoselective dual functionalization of proteins is an invaluable tool to introduce two distinct payloads to proteins. Here, the authors present N-alkylpyridinium reagents as soft electrophiles for c...
www.nature.com
June 9, 2025 at 9:06 AM