Maria Cavallaro
@mariacav6.bsky.social
PhD Student at Dartmouth College
#tumorimmunology #adaptiveimmunity #immunememory
#tumorimmunology #adaptiveimmunity #immunememory
Reposted by Maria Cavallaro
Expansion of tumor-reactive CD8+ T cell clonotypes occurs in the spleen in response to immune checkpoint blockade | Science Immunology www.science.org/doi/10.1126/...
Expansion of tumor-reactive CD8+ T cell clonotypes occurs in the spleen in response to immune checkpoint blockade
Response to ICB depends on optimal splenic antigen levels, whereas increased antigen induces differentiation to circulatory T cells.
www.science.org
February 28, 2025 at 9:15 PM
Expansion of tumor-reactive CD8+ T cell clonotypes occurs in the spleen in response to immune checkpoint blockade | Science Immunology www.science.org/doi/10.1126/...
Reposted by Maria Cavallaro
Published a new piece on Biohackers Media, T-bet's Role in Enhancing Memory B Cells
#science #longevity #biohacking
#science #longevity #biohacking
T-bet's Role in Enhancing Memory B Cells
Study reveals T-bet's vital role in enhancing long-term memory B cells for improved flu immunity and vaccine efficacy.
biohackers.media
July 12, 2025 at 11:00 AM
Published a new piece on Biohackers Media, T-bet's Role in Enhancing Memory B Cells
#science #longevity #biohacking
#science #longevity #biohacking
Reposted by Maria Cavallaro
"Here, we use paired single-cell transcriptome and Variable, Diversity, and Joining (VDJ) sequencing to measure the phenotypic and genetic relationships of B cells in four immune-rich tissues in six healthy individuals."
#Immunology #Immunosky
www.pnas.org/doi/10.1073/...
#Immunology #Immunosky
www.pnas.org/doi/10.1073/...
Long-term B cell memory emerges at uniform relative rates in the human immune response | PNAS
B cells generate pathogen-specific antibodies and play an essential role in providing
adaptive protection against infection. Antibody genes are mod...
www.pnas.org
March 31, 2025 at 5:55 AM
"Here, we use paired single-cell transcriptome and Variable, Diversity, and Joining (VDJ) sequencing to measure the phenotypic and genetic relationships of B cells in four immune-rich tissues in six healthy individuals."
#Immunology #Immunosky
www.pnas.org/doi/10.1073/...
#Immunology #Immunosky
www.pnas.org/doi/10.1073/...
Reposted by Maria Cavallaro
Metallophilic CD169+ marginal zone macrophages cross-prime CD8+ T cell-mediated protective immunity against blood-borne tumors using a proteasome- and cDC1-independent pathway @cp-immunity.bsky.social
www.cell.com/immunity/ful...
www.cell.com/immunity/ful...
March 27, 2025 at 4:25 AM
Metallophilic CD169+ marginal zone macrophages cross-prime CD8+ T cell-mediated protective immunity against blood-borne tumors using a proteasome- and cDC1-independent pathway @cp-immunity.bsky.social
www.cell.com/immunity/ful...
www.cell.com/immunity/ful...
Reposted by Maria Cavallaro
From 2010 to 2016 (latest data I have ), NIH research contributed to EVERY drug approved by the FDA
March 22, 2025 at 10:44 AM
From 2010 to 2016 (latest data I have ), NIH research contributed to EVERY drug approved by the FDA