Margherita Malanchini
@marghmalanchini.bsky.social
Developmental psychologist at QMUL. Director of the Cognition, Development and Education research lab (http://codelab.science). Mum of 2. She/her
Research and interventions focused solely on transdiagnostic risk are unlikely to capture the full complexity of these relationships or to enhance our understanding of the distinct cognitive profiles associated with different psychiatric conditions.
June 10, 2025 at 9:51 AM
Research and interventions focused solely on transdiagnostic risk are unlikely to capture the full complexity of these relationships or to enhance our understanding of the distinct cognitive profiles associated with different psychiatric conditions.
4️⃣ Within-sibling analyses indicated that genetic associations operated through distinct pathways: for some disorders (e.g., ADHD), effects were largely shared between siblings, while for others (e.g., ASD), they were specific to each individual within a family.
June 10, 2025 at 9:51 AM
4️⃣ Within-sibling analyses indicated that genetic associations operated through distinct pathways: for some disorders (e.g., ADHD), effects were largely shared between siblings, while for others (e.g., ASD), they were specific to each individual within a family.
2️⃣ While for some psychiatric disorders (e.g., ADHD, Tourette’s) associations with cognitive skills were negative, for others (e.g., autism spectrum disorder, anorexia nervosa) they were positive.
3️⃣ Associations increased across development and varied for different cognitive skills.
3️⃣ Associations increased across development and varied for different cognitive skills.
June 10, 2025 at 9:51 AM
2️⃣ While for some psychiatric disorders (e.g., ADHD, Tourette’s) associations with cognitive skills were negative, for others (e.g., autism spectrum disorder, anorexia nervosa) they were positive.
3️⃣ Associations increased across development and varied for different cognitive skills.
3️⃣ Associations increased across development and varied for different cognitive skills.
The results showed that:
1️⃣ The relationship between psychopathology and cognitive functioning is primarily driven by disorder-specific genetic effects, rather than by transdiagnostic factors.
1️⃣ The relationship between psychopathology and cognitive functioning is primarily driven by disorder-specific genetic effects, rather than by transdiagnostic factors.
June 10, 2025 at 9:51 AM
The results showed that:
1️⃣ The relationship between psychopathology and cognitive functioning is primarily driven by disorder-specific genetic effects, rather than by transdiagnostic factors.
1️⃣ The relationship between psychopathology and cognitive functioning is primarily driven by disorder-specific genetic effects, rather than by transdiagnostic factors.
🧠🧬🧑🤝🧑 New CoDE Lab study: Disorder-specific genetic effects drive the associations between psychopathology and cognitive functioning. Link to preprint: www.medrxiv.org/content/10.1... Led by the brilliant Wangjingyi Liao 🌟
A short thread summarising the study👇
A short thread summarising the study👇
June 10, 2025 at 9:51 AM
🧠🧬🧑🤝🧑 New CoDE Lab study: Disorder-specific genetic effects drive the associations between psychopathology and cognitive functioning. Link to preprint: www.medrxiv.org/content/10.1... Led by the brilliant Wangjingyi Liao 🌟
A short thread summarising the study👇
A short thread summarising the study👇
7/9. Mediation effects could also be observed when examining differences between siblings. Examining differences between siblings we were able to separate the effects of family-wide processes from those unique to each child within a family.
February 28, 2025 at 10:59 AM
7/9. Mediation effects could also be observed when examining differences between siblings. Examining differences between siblings we were able to separate the effects of family-wide processes from those unique to each child within a family.
6/9. 🔷 Time-lagged analyses showed that the mediating role of non-cognitive skills persisted across development, underscoring the importance of fostering non-cognitive skills to enhance students’ long-term academic outcomes.
February 28, 2025 at 10:59 AM
6/9. 🔷 Time-lagged analyses showed that the mediating role of non-cognitive skills persisted across development, underscoring the importance of fostering non-cognitive skills to enhance students’ long-term academic outcomes.
5/9/ 🔷 non-cognitive skills, particularly those characteristics closely linked to learning (e.g., academic interest, curiosity, and academic self-perceived ability), play a critical role in translating education-associated genetic dispositions into observed academic achievement.
February 28, 2025 at 10:59 AM
5/9/ 🔷 non-cognitive skills, particularly those characteristics closely linked to learning (e.g., academic interest, curiosity, and academic self-perceived ability), play a critical role in translating education-associated genetic dispositions into observed academic achievement.
New CoDE Lab preprint. We investigated whether spatial ability consistently predicts STEM success beyond other cognitive skills and what aspects of spatial ability predict success in STEM more accurately. Link: www.biorxiv.org/content/10.1...
January 6, 2025 at 4:21 PM
New CoDE Lab preprint. We investigated whether spatial ability consistently predicts STEM success beyond other cognitive skills and what aspects of spatial ability predict success in STEM more accurately. Link: www.biorxiv.org/content/10.1...
First 🦋 post. New preprint: “Gene-environment correlation: The role of family environment in academic development”. We investigate how family environments contribute to translating genetic dispositions into observed differences in academic achievement across development. biorxiv.org/cgi/content/...
January 9, 2024 at 4:50 PM
First 🦋 post. New preprint: “Gene-environment correlation: The role of family environment in academic development”. We investigate how family environments contribute to translating genetic dispositions into observed differences in academic achievement across development. biorxiv.org/cgi/content/...