Bhavesh Valecha
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mardybhavesh.bsky.social
Bhavesh Valecha
@mardybhavesh.bsky.social
PhD Candidate studying nonequilibrium statistical physics @Univeristy of Augsburg
This brings me to the end of a number of firsts - first #bluesky post, first thread, first PhD publications. Thanks for reading :') 12/12
September 7, 2025 at 8:11 AM
Check out more details here:
pubs.rsc.org/en/content/a...
Big thanks to Shashank Ravichandir and colleagues at IPF Dresden for this collaboration :) 11/n
Transport of partially active polymers in chemical gradients
The transport of molecules for chemical reactions is critically important in various cellular biological processes. Despite thermal diffusion being prevalent in many biochemical processes, it is unrel...
pubs.rsc.org
September 7, 2025 at 8:11 AM
Furthermore, we find that the dynamics of these chains is also affected by the number and location of active units. We report this using the mean first passage time required to reach location of highest activity, which decreases with increasing number of active units. 10/n
September 7, 2025 at 8:11 AM
We report that different locations and number of active units in the chain lead to different accumulation behaviour. Surprisingly, chains with fewer active units do better than chains uniquely composed of ABPs. 9/n
September 7, 2025 at 8:11 AM
We again consider this system in activity gradients and want to determine if the accumulation behavior can be controlled by the location and number of active units in the chain. Further, we also check how the dynamics are affected by the same metric,i.e. are chains with more active units faster? 8/n
September 7, 2025 at 8:11 AM
Next, to study systems akin to chromosomal loci, we consider active Rouse chains, composed of both ABPs and passive ones. The presence of ABPs in only parts of the chain is inspired by the presence of active components like kinesin motors stressing certain parts of an otherwise passive network. 7/n
September 7, 2025 at 8:11 AM
Check out the nitty-gritties of this study here
pubs.rsc.org/en/content/a...
Thankful to Dr. Hossein Vahid at IPF Dresden for this fruitful collaboration :) 6/n
Active transport of cargo-carrying and interconnected chiral particles
Directed motion up a concentration gradient is crucial for the survival and maintenance of numerous biological systems, such as sperms moving towards an egg during fertilization or ciliates moving tow...
pubs.rsc.org
September 7, 2025 at 8:11 AM
Moreover, with a large enough chiral torque composites with small passive counterpart can also accumulate in high activity. This goes further than previous studies (PRL 126, 208102) where accumulation in high activity was possible only beyond a certain size of the passive part of the composite. 5/n
September 7, 2025 at 8:11 AM
Starting with stochastic differential equations followed by coarse graining, we find that the accumulation behaviour can be tuned using the chiral torque. This gives another handle on controlling the accumulation of ABPs, complementing new experimental setups with magnetotactic swimmers. 4/n
September 7, 2025 at 8:11 AM
First, to capture the rotational aspect of sperm motion, we consider the simple case of a chiral active Brownian particle (cABP) connected to a passive one. This system is in an activity gradient to simulate chemical gradients, and we want to know where this system migrates to and accumulates. 3/n
September 7, 2025 at 8:11 AM
Not only in cartoons, but this directed motion is prevalent in many biological systems, for eg, sperms migrating towards egg during fertilisation, and chromosomal loci dynamics during interphase. Motivated by these examples, we try to model them using standard active matter models in two studies 2/n
September 7, 2025 at 8:11 AM