Marcus Low
@marcuslowx.bsky.social
Novelist, editor of Spotlight, aspiring epidemiologist, lover of labradors.
I suspect there will be some truly fascinating presentations of data from this study at conferences 3 or 4 years from now.
There is still much uncertainty over how asymptomatic TB functions in the body and how infectious it is. An ambitious study, set to be conducted in South Africa and Indonesia, is trying to find some answers, reports @elri-voigt.bsky.social.
www.spotlightnsp.co.za/2025/11/06/s...
www.spotlightnsp.co.za/2025/11/06/s...
SA and Indonesia team up on massive asymptomatic TB study
Over the last decade, there’s been growing evidence that people can have TB without having any symptoms. But there is still much uncertainty over how such asymptomatic TB functions in the body and how...
www.spotlightnsp.co.za
November 6, 2025 at 11:31 AM
I suspect there will be some truly fascinating presentations of data from this study at conferences 3 or 4 years from now.
Reposted by Marcus Low
MUST READ | The number of HIV viral load tests recorded by the National Health Laboratory Service is significantly less than expected since Feb 2025. Spotlight and @groundup.org.za are aware of no compelling reason to explain this except the US aid withdrawal.
www.spotlightnsp.co.za/2025/11/04/w...
www.spotlightnsp.co.za/2025/11/04/w...
Withdrawal of US aid has hurt South Africa’s HIV programme
The number of HIV viral load tests is significantly lower than expected, according to an analysis of data from the National Health Laboratory Service which Spotlight and GroundUp obtained through the ...
www.spotlightnsp.co.za
November 4, 2025 at 6:18 AM
MUST READ | The number of HIV viral load tests recorded by the National Health Laboratory Service is significantly less than expected since Feb 2025. Spotlight and @groundup.org.za are aware of no compelling reason to explain this except the US aid withdrawal.
www.spotlightnsp.co.za/2025/11/04/w...
www.spotlightnsp.co.za/2025/11/04/w...
The second in our series on the key legal questions on which the NHI court cases are likely to turn. Great work from Jesse Copelyn, as always.
NHI NEWS | The NHI Act is facing a slew of legal challenges. Spotlight combed through court papers, and spoke with legal experts to pin down what specific arguments litigants are betting on.
www.spotlightnsp.co.za/2025/10/29/o...
www.spotlightnsp.co.za/2025/10/29/o...
On which legal arguments are the NHI court cases set to turn? Part 2: Right to healthcare services
The NHI Act is facing a slew of legal challenges from multiple organisations. For this special series, Spotlight combed through court papers, and spoke with legal experts to pin down what specific arg...
www.spotlightnsp.co.za
October 30, 2025 at 9:43 AM
The second in our series on the key legal questions on which the NHI court cases are likely to turn. Great work from Jesse Copelyn, as always.
Catherine Tomlinson on what still needs to happen before pharmacists can dispense ARVs without a script from a Dr.
MONDAY MUST READ | Pharmacists with the required training will need special permits to dispense antiretrovirals without a doctor’s script. Spotlight reports that they may be able to start applying for these permits as soon as next month.
www.spotlightnsp.co.za/2025/10/27/p...
www.spotlightnsp.co.za/2025/10/27/p...
ARVs without a script: What next after major court ruling?
A landmark ruling from the Supreme Court of Appeal means specially trained pharmacists will soon be allowed to dispense antiretrovirals without a doctor’s script. Pharmacists with the required trainin...
www.spotlightnsp.co.za
October 27, 2025 at 9:34 AM
Catherine Tomlinson on what still needs to happen before pharmacists can dispense ARVs without a script from a Dr.
Reposted by Marcus Low
BIG SA NEWS IN HIV PREVENTION | Our medicines regulator approved an HIV prevention shot containing lenacapavir. It provides protection for six months with a single dose. A limited public rollout is set for April 2026.
www.spotlightnsp.co.za/2025/10/27/b...
www.spotlightnsp.co.za/2025/10/27/b...
October 27, 2025 at 9:27 AM
BIG SA NEWS IN HIV PREVENTION | Our medicines regulator approved an HIV prevention shot containing lenacapavir. It provides protection for six months with a single dose. A limited public rollout is set for April 2026.
www.spotlightnsp.co.za/2025/10/27/b...
www.spotlightnsp.co.za/2025/10/27/b...
These briefings are of the best things we publish on Spotlight
MUST READ | Childhood immunisation programmes have saved millions of lives. Today, these vital efforts are losing momentum. In this #InTheSpotlight feature, @elri-voigt.bsky.social unpacks the data and explores how to revive these life-saving programmes.
www.spotlightnsp.co.za/2025/10/13/i...
www.spotlightnsp.co.za/2025/10/13/i...
#InTheSpotlight | Amid all the noise, how well is SA’s immunisation programme actually doing
Childhood immunisation programmes have saved many millions of lives and prevented much suffering. Yet, immunisation programmes have lost momentum over the last decade or so. In this #InTheSpotlight sp...
www.spotlightnsp.co.za
October 13, 2025 at 11:09 AM
These briefings are of the best things we publish on Spotlight
Reposted by Marcus Low
MUST READ | Deep into the night while most of Cape Town is asleep, trauma surgeon Dr Deidre McPherson slips into work scrubs, hitting the highway to Groote Schuur Hospital to save the lives of critically injured patients.
www.spotlightnsp.co.za/2025/10/03/b...
www.spotlightnsp.co.za/2025/10/03/b...
Between silence and sirens: Cape Town trauma surgeon Dr Deidre McPherson’s midnight vigils
Groote Schuur Hospital in Cape Town has one of the busiest emergency centres in the Western Cape. As it turns to the public to raise R20 million for the opening of a new emergency centre, Dr Deidre Mc...
www.spotlightnsp.co.za
October 6, 2025 at 9:42 AM
MUST READ | Deep into the night while most of Cape Town is asleep, trauma surgeon Dr Deidre McPherson slips into work scrubs, hitting the highway to Groote Schuur Hospital to save the lives of critically injured patients.
www.spotlightnsp.co.za/2025/10/03/b...
www.spotlightnsp.co.za/2025/10/03/b...
Good article by Catherine Tomlinson. One of the reasons Spotlight exists is to publish clear explainers like this on important but under covered health issues.
DID YOU KNOW? Medical devices aren’t regulated in SA. The country's regulator has however started down a road that should eventually lead to the regulation of all medical devices.
www.spotlightnsp.co.za/2025/10/01/m...
www.spotlightnsp.co.za/2025/10/01/m...
Medical devices aren’t regulated in SA, but that is set to change
Unlike with medicines, and with a few exceptions, South Africa’s regulator does not assess whether diagnostic tests and other medical devices on the market are safe and work as they are supposed to. T...
www.spotlightnsp.co.za
October 1, 2025 at 8:47 AM
Good article by Catherine Tomlinson. One of the reasons Spotlight exists is to publish clear explainers like this on important but under covered health issues.
Reposted by Marcus Low
The Gauteng health department has an annual budget of around R67 billion. This is more than 20% of the South African government’s entire spending on health. For the corrupt, the Gauteng health department is an obvious target.
www.spotlightnsp.co.za/2025/09/19/e...
www.spotlightnsp.co.za/2025/09/19/e...
EDITORIAL | The rot runs deep: Gauteng Health’s dance of impunity betrays the people it is meant to serve
The courts have spoken. The health ombud has issued devastating reports. The Auditor-General has again put damning evidence on the table. Civil society has protested. Yet, the devastating crisis in Ga...
www.spotlightnsp.co.za
September 19, 2025 at 11:04 AM
The Gauteng health department has an annual budget of around R67 billion. This is more than 20% of the South African government’s entire spending on health. For the corrupt, the Gauteng health department is an obvious target.
www.spotlightnsp.co.za/2025/09/19/e...
www.spotlightnsp.co.za/2025/09/19/e...
Reposted by Marcus Low
NHI PUSHBACK | A key argument in challenging the NHI ACT in court is that it's irrational and unreasonable to overhaul the health system when there’s no money to do so. Spotlight dissects how the argument is being applied.
www.spotlightnsp.co.za/2025/09/16/o...
www.spotlightnsp.co.za/2025/09/16/o...
On which legal arguments are the NHI court cases set to turn? Part 1: Affordability
Since President Cyril Ramaphposa signed the NHI Act into law last year in May, eight different groups have challenged it in court. One common argument is that it is irrational and unreasonable to rest...
www.spotlightnsp.co.za
September 16, 2025 at 7:48 AM
NHI PUSHBACK | A key argument in challenging the NHI ACT in court is that it's irrational and unreasonable to overhaul the health system when there’s no money to do so. Spotlight dissects how the argument is being applied.
www.spotlightnsp.co.za/2025/09/16/o...
www.spotlightnsp.co.za/2025/09/16/o...
Reposted by Marcus Low
Incredible article on a fascinating case of a pregnancy bridging the Gugulethu Midwife Obstetrics Unit, Mowbray Maternity Hospital and Groote Schuur Hospital – a real health systems success story!
www.spotlightnsp.co.za/2025/09/08/h...
@uct-fhs-research.bsky.social @spotlightnsp.bsky.social
www.spotlightnsp.co.za/2025/09/08/h...
@uct-fhs-research.bsky.social @spotlightnsp.bsky.social
How a Cape Town mother gave birth to ‘miracle baby’ who grew outside her womb
Joshua was safely delivered from Sylvia’s belly instead of her uterus one year ago. Biénne Huisman meets mother and baby, and hears from some of the healthcare professionals involved in the remarkable...
www.spotlightnsp.co.za
September 9, 2025 at 8:46 AM
Incredible article on a fascinating case of a pregnancy bridging the Gugulethu Midwife Obstetrics Unit, Mowbray Maternity Hospital and Groote Schuur Hospital – a real health systems success story!
www.spotlightnsp.co.za/2025/09/08/h...
@uct-fhs-research.bsky.social @spotlightnsp.bsky.social
www.spotlightnsp.co.za/2025/09/08/h...
@uct-fhs-research.bsky.social @spotlightnsp.bsky.social
Some very good news here
HIV & KIDS | The potent antiretroviral drug dolutegravir has become the backbone of SA’s HIV treatment programme. New estimates suggest that most children aged one to four living with HIV have now been switched to the drug, reports @elri-voigt.bsky.social.
www.spotlightnsp.co.za/2025/09/04/t...
www.spotlightnsp.co.za/2025/09/04/t...
Thousands of kids with HIV switched to newer treatment
A child-friendly formulation of the antiretroviral drug dolutegravir was first included in the country’s HIV treatment guidelines in 2023. New estimates suggest that most children aged one to four liv...
www.spotlightnsp.co.za
September 4, 2025 at 9:23 AM
Some very good news here
Reposted by Marcus Low
Only three in every ten former miners claiming compensation from the R5-billion Tshiamiso Trust have been compensated, the Trust’s CEO Munyadziwa Kwinda told the online AGM last month. Most have been found to be medically ineligible.
Read groundup.org.za/article/comp... by Sipokazi Fokazi
Read groundup.org.za/article/comp... by Sipokazi Fokazi
Compensation for sick miners: only 30% of claimants paid out by Tshiamiso Trust
Most claims do not meet the medical criteria, AGM told
groundup.org.za
September 4, 2025 at 8:16 AM
Only three in every ten former miners claiming compensation from the R5-billion Tshiamiso Trust have been compensated, the Trust’s CEO Munyadziwa Kwinda told the online AGM last month. Most have been found to be medically ineligible.
Read groundup.org.za/article/comp... by Sipokazi Fokazi
Read groundup.org.za/article/comp... by Sipokazi Fokazi
Reposted by Marcus Low
MUST READ | The health department plans to roll out lenacapavir, a twice-yearly HIV prevention injection in 2026. Yet, little progress has been made towards rolling out a two-monthly prevention injection, despite the four-year head start on lenacapavir.
www.spotlightnsp.co.za/2025/09/02/t...
www.spotlightnsp.co.za/2025/09/02/t...
Twists and turns in the race to be SA’s first widely used HIV prevention injection
The health department has plans to roll out lenacapavir, a twice-yearly HIV prevention injection, in a select group of public sector clinics by April 2026. Meanwhile, little progress has been made tow...
www.spotlightnsp.co.za
September 2, 2025 at 7:26 AM
MUST READ | The health department plans to roll out lenacapavir, a twice-yearly HIV prevention injection in 2026. Yet, little progress has been made towards rolling out a two-monthly prevention injection, despite the four-year head start on lenacapavir.
www.spotlightnsp.co.za/2025/09/02/t...
www.spotlightnsp.co.za/2025/09/02/t...
Reposted by Marcus Low
CRIPPLING CUTS | Doctors have blown the whistle about a crisis at one of KwaZulu-Natal’s most important public hospitals, saying it is functioning far under capacity due to a series of cuts that they say is costing lives.
www.spotlightnsp.co.za/2025/09/01/w...
www.spotlightnsp.co.za/2025/09/01/w...
‘We can’t save them anymore’: Doctors raise alarm about crippling cuts at major KZN hospital
Doctors have blown the whistle about a crisis at one of KwaZulu-Natal’s most important public hospitals, saying it is functioning far under capacity due to a series of crippling cuts. Chris Bateman re...
www.spotlightnsp.co.za
September 1, 2025 at 12:31 PM
CRIPPLING CUTS | Doctors have blown the whistle about a crisis at one of KwaZulu-Natal’s most important public hospitals, saying it is functioning far under capacity due to a series of cuts that they say is costing lives.
www.spotlightnsp.co.za/2025/09/01/w...
www.spotlightnsp.co.za/2025/09/01/w...
Reposted by Marcus Low
In his latest #InsideTheBox column, Dr Andy Gray explains how reliance mechanisms can help regulators make decisions more quickly and efficiently, and digs into the details of how South Africa can make the most of these mechanisms.
www.spotlightnsp.co.za/2025/08/25/i...
www.spotlightnsp.co.za/2025/08/25/i...
#InsideTheBox with Dr Andy Gray | How could more efficient use of reliance improve access to quality, affordable medicines?
Rather than trying to do everything from scratch, medicines regulators from different countries are increasingly sharing the load between them by ‘relying’ on each other’s work. In his latest #InsideT...
www.spotlightnsp.co.za
August 25, 2025 at 7:42 AM
In his latest #InsideTheBox column, Dr Andy Gray explains how reliance mechanisms can help regulators make decisions more quickly and efficiently, and digs into the details of how South Africa can make the most of these mechanisms.
www.spotlightnsp.co.za/2025/08/25/i...
www.spotlightnsp.co.za/2025/08/25/i...
Reposted by Marcus Low
Statistics released this month confirmed that 140,000 more South Africans became unemployed between April and June, taking our unemployment rate to a scary 33.2%.
Read groundup.org.za/article/nati... by Noncedo Madubedube
Read groundup.org.za/article/nati... by Noncedo Madubedube
National Dialogue: let’s listen to young people, not to the political elite
A view from the National Convention
groundup.org.za
August 25, 2025 at 9:42 AM
Statistics released this month confirmed that 140,000 more South Africans became unemployed between April and June, taking our unemployment rate to a scary 33.2%.
Read groundup.org.za/article/nati... by Noncedo Madubedube
Read groundup.org.za/article/nati... by Noncedo Madubedube
Reposted by Marcus Low
BATTLE TO BREATHE | Despite a landmark court ruling that upheld the right to clean air, air pollution remains rife in Emalahleni. For part 2 of this Spotlight special series, reporter Sue Segar and photographer Thom Pierce met up with activists in Mpumalanga.
www.spotlightnsp.co.za/2025/08/18/b...
www.spotlightnsp.co.za/2025/08/18/b...
Battle to breathe: The ongoing struggle for clean air in Mpumalanga
Despite a landmark court judgment three years ago that upheld the right to clean air, air pollution remains rife in South Africa’s coal country. For part 2 of this Spotlight special series, journalist...
www.spotlightnsp.co.za
August 18, 2025 at 6:31 AM
BATTLE TO BREATHE | Despite a landmark court ruling that upheld the right to clean air, air pollution remains rife in Emalahleni. For part 2 of this Spotlight special series, reporter Sue Segar and photographer Thom Pierce met up with activists in Mpumalanga.
www.spotlightnsp.co.za/2025/08/18/b...
www.spotlightnsp.co.za/2025/08/18/b...
Reposted by Marcus Low
BATTLE TO BREATHE | Emalahleni translates to ‘place of coal’. But for many people living here, it has also become a place of dirty air. To get first-hand accounts of their stories, Writer Susan Segar and photographer Thom Pierce travelled to Mpumalanga.
www.spotlightnsp.co.za/2025/08/04/b...
www.spotlightnsp.co.za/2025/08/04/b...
August 4, 2025 at 7:39 AM
BATTLE TO BREATHE | Emalahleni translates to ‘place of coal’. But for many people living here, it has also become a place of dirty air. To get first-hand accounts of their stories, Writer Susan Segar and photographer Thom Pierce travelled to Mpumalanga.
www.spotlightnsp.co.za/2025/08/04/b...
www.spotlightnsp.co.za/2025/08/04/b...
Interesting story from the US. For comparison, here is our reporting on how the price of lenalidomide (revlimid) has fluctuated in SA https://www.spotlightnsp.co.za/2023/02/15/analysis-why-has-the-price-of-this-cancer-medicine-risen-and-fallen-by-over-a-thousand-percent-since-2016/
Revlimid has its origin in a pill that cost patients $7.50 each. Decades later, the cancer drug costs more than $18,000 for a month’s supply — even though it still only costs about 25 cents to manufacture.
(Published May)
By @davidarmstrongx.bsky.social
(Published May)
By @davidarmstrongx.bsky.social
The Price of Remission: This Cancer Drug Saves Lives — but Costs a Fortune. I Wanted to Know Why.
When I was diagnosed with cancer, I set out to understand why a single pill of Revlimid cost the same as a new iPhone. I’ve covered high drug prices as a reporter for years. What I discovered shocked…
www.propublica.org
July 31, 2025 at 6:12 AM
Interesting story from the US. For comparison, here is our reporting on how the price of lenalidomide (revlimid) has fluctuated in SA https://www.spotlightnsp.co.za/2023/02/15/analysis-why-has-the-price-of-this-cancer-medicine-risen-and-fallen-by-over-a-thousand-percent-since-2016/
If this monthly PrEP pill does well in phase 3 it could, probably should, become as big a deal as lenacapavir.
HIV prevention options has come a long way with a daily pill, injections lasting 2 or 6 months, and a monthly ring for women. A monthly pill could change the game even more, reports @elri-voigt.bsky.social.
www.spotlightnsp.co.za/2025/07/25/i...
www.spotlightnsp.co.za/2025/07/25/i...
IAS2025: Findings give hope for monthly HIV prevention pill
An HIV prevention pill that could provide a month of protection per tablet has been given the green light to proceed to pivotal trials to test its efficacy. Elri Voigt reports on new findings on the p...
www.spotlightnsp.co.za
July 29, 2025 at 6:06 AM
If this monthly PrEP pill does well in phase 3 it could, probably should, become as big a deal as lenacapavir.
I’m very happy that we get to publish these very informative monthly columns from Dr Andy Gray. I have learned a lot from them.
Anyone who has travelled to the US will have been struck by the extent to which medicines are advertised on television. The situation in South Africa is quite different, writes Dr Andy Gray in his latest #InsideTheBox column.
www.spotlightnsp.co.za/2025/07/28/i...
www.spotlightnsp.co.za/2025/07/28/i...
#InsideTheBox with Dr Andy Gray | Should pharmaceutical advertising in SA be better regulated, and why?
For over 20 years, the law has required that the Minister of Health issues regulations to govern the advertising of medicines in South Africa, but as yet no such regulations are in place. In his lates...
www.spotlightnsp.co.za
July 29, 2025 at 6:03 AM
I’m very happy that we get to publish these very informative monthly columns from Dr Andy Gray. I have learned a lot from them.
Could AI slow science? From the always interesting Narayanan and Kapoor https://www.aisnakeoil.com/p/could-ai-slow-science?post_id=168505690&r=4q9dc1&utm_source=substack Could AI slow science?
July 17, 2025 at 12:36 PM
Could AI slow science? From the always interesting Narayanan and Kapoor https://www.aisnakeoil.com/p/could-ai-slow-science?post_id=168505690&r=4q9dc1&utm_source=substack Could AI slow science?
Some great and accessible explanations in here of how TB and TB treatments work.
MUST READ | TB can be cured, but ridding the body of the bug often takes many months. In this Spotlight special briefing, @elri-voigt.bsky.social zoom in on what makes the TB bacterium so hard to beat.
www.spotlightnsp.co.za/2025/07/14/i...
www.spotlightnsp.co.za/2025/07/14/i...
#InTheSpotlight | TB’s tight grip: Why this curable disease is so hard to treat
TB can be cured, but ridding the body of the bug often takes many months and usually requires taking four or more different medicines. In this Spotlight special briefing, Elri Voigt zooms in on what m...
www.spotlightnsp.co.za
July 15, 2025 at 7:46 AM
Some great and accessible explanations in here of how TB and TB treatments work.
Reposted by Marcus Low
VACCINES | The National Department of Health is currently reviewing a recommendation by the country’s advisory group on immunisations to make a new RSV vaccine available to all pregnant women.
www.spotlightnsp.co.za/2025/07/15/g...
www.spotlightnsp.co.za/2025/07/15/g...
Government is considering providing a vaccine to protect babies from RSV
A new respiratory syncytial virus vaccine to protect infants from severe illness is available in South Africa’s private sector but not yet in public clinics. The country's advisory group on immunisati...
www.spotlightnsp.co.za
July 15, 2025 at 7:26 AM
VACCINES | The National Department of Health is currently reviewing a recommendation by the country’s advisory group on immunisations to make a new RSV vaccine available to all pregnant women.
www.spotlightnsp.co.za/2025/07/15/g...
www.spotlightnsp.co.za/2025/07/15/g...