Marc Tollis
@marcanthonytollis.bsky.social
Evolutionary biologist from Queens. Genomes, phylogenies, TEs, cancer. Musician/drummer, dinosaur. I got kids. Former museum educator. Associate professor at Northern Arizona University
Have a read, hope you enjoy! www.biorxiv.org/content/10.1...
Recent Non-LTR Retrotransposon Activity Predicts Cancer Prevalence in Mammals
Non-long terminal repeat retrotransposons (nLTRs), including long and short interspersed nuclear elements (L1 and SINEs), are the most abundant and active mobile elements in mammals. NLTRs play critic...
www.biorxiv.org
September 5, 2025 at 2:53 AM
Have a read, hope you enjoy! www.biorxiv.org/content/10.1...
This suggests that LINE movement in the genome promotes tumor growth, but once SINEs, which depend on LINE enzymatic machinery, get moving, that’s what causes trouble (i.e. malignant cancers)
a close up of a man 's face with a gmail.com email address
ALT: a close up of a man 's face with a gmail.com email address
media.tenor.com
September 5, 2025 at 2:53 AM
This suggests that LINE movement in the genome promotes tumor growth, but once SINEs, which depend on LINE enzymatic machinery, get moving, that’s what causes trouble (i.e. malignant cancers)
Interestingly, he found that across mammals LINE activity predicts neoplasia prevalence, but when you add SINEs to the mix, it predicts malignancy
a group of men in monkey costumes with the caption you and me baby aint nothin but mammals
ALT: a group of men in monkey costumes with the caption you and me baby aint nothin but mammals
media.tenor.com
September 5, 2025 at 2:53 AM
Interestingly, he found that across mammals LINE activity predicts neoplasia prevalence, but when you add SINEs to the mix, it predicts malignancy
We are still doing the negotiated F&A.
Yeah my summer plan was to put in a grant by August but I’m changing course to focus on beefing up the preliminary work, and push it into the fall.
Provided there is an NSF DEB by then.
Yeah my summer plan was to put in a grant by August but I’m changing course to focus on beefing up the preliminary work, and push it into the fall.
Provided there is an NSF DEB by then.
May 10, 2025 at 10:27 PM
We are still doing the negotiated F&A.
Yeah my summer plan was to put in a grant by August but I’m changing course to focus on beefing up the preliminary work, and push it into the fall.
Provided there is an NSF DEB by then.
Yeah my summer plan was to put in a grant by August but I’m changing course to focus on beefing up the preliminary work, and push it into the fall.
Provided there is an NSF DEB by then.
Sophie came to NAU from Ireland to work on this project one fall, to follow up on on a study we published in 2020 (also in MBE). It couldn't have gone better, and the new paper is a welcome contribution to the cancer evolution literature. oup2-idp.sams-sigma.com/authorize?au...
The Evolution of Human Cancer Gene Duplications across Mammals
Abstract. Cancer is caused by genetic alterations that affect cellular fitness, and multicellular organisms have evolved mechanisms to suppress cancer such
oup2-idp.sams-sigma.com
March 22, 2025 at 5:31 PM
Sophie came to NAU from Ireland to work on this project one fall, to follow up on on a study we published in 2020 (also in MBE). It couldn't have gone better, and the new paper is a welcome contribution to the cancer evolution literature. oup2-idp.sams-sigma.com/authorize?au...
I don’t know why (well, money). Superman (1978) is a perfect movie and still holds up
December 20, 2024 at 1:28 AM
I don’t know why (well, money). Superman (1978) is a perfect movie and still holds up
It doesn’t get easier. They stay difficult, except are huge, mobile, and extremely talkative (until they become teenagers and stop talking for a little while)
December 18, 2024 at 3:24 PM
It doesn’t get easier. They stay difficult, except are huge, mobile, and extremely talkative (until they become teenagers and stop talking for a little while)