Mara Burns
banner
maraburns1.bsky.social
Mara Burns
@maraburns1.bsky.social
Neuroscience PhD Candidate @ UC Irvine | Dr. Leslie Thompson's Lab | CIRM Scholars Trainee | F31 NINDS | ARCS Foundation Scholar | VP @HDCARE3
It’s been a month!
First author paper published in Neuron
Mark and I are engaged!
Presented at an international conference in Italy where my love and I traveled around after exploring Cinque Terre and Tuscany 🥰
Received the Allergan BioSci Graduate Award and GDDF*
I’m over the freaking moon!
June 11, 2025 at 5:05 PM
Sitting in a cafe in San Gimignano Italy when I realized that my first first-author publication is now available online in Neuron!!! Check out our temporal spatial transcriptomics findings in the Huntington's disease R6/2 mouse. 🥰

Read here: www.cell.com/neuron/fullt...
Distinct molecular patterns in R6/2 HD mouse brain: Insights from spatiotemporal transcriptomics
Burns et al. conduct longitudinal spatial sequencing integrated with single-nuclei RNA sequencing in a Huntington’s disease mouse model, revealing early cell and regional changes. Their findings provi...
www.cell.com
June 6, 2025 at 3:34 PM
So excited to see my fantastic boss, Dr. Leslie Thompson, on TV, along with a Huntington's disease patient speaking about the impact of HD and hope for the future. Check it out! ktla.com/news/local-n...
Orange County woman opens up about living with fatal, rare Huntington’s disease
An Orange County woman is opening up about what it’s like to live with a fatal, rare disease that’s been compared to having ALS, Parkinson’s and Alzheimer’s all at once. Carrie Bryson, a 61-y…
ktla.com
May 14, 2025 at 6:47 PM
Reposted by Mara Burns
We're disappointed to see Ben Barres's powerful book "The Autobiography of a Transgender Scientist" among the ~400 titles removed from the Naval Academy Library. Needless to say, we're proud to have published his book and will keep it — and his memory — alive.
The Coming Out of a Transgender Scientist
"I know that I am making the right decision because whenever I think about changing my gender role, I am flooded with feelings of relief."
thereader.mitpress.mit.edu
April 8, 2025 at 8:24 PM
I have attended the UCI REMIND symposium for the past 5 years and this year I had the pleasure of presenting my work on Friday! Thanks to everyone who attended. 🔬
March 5, 2025 at 4:48 PM
My best friend defended his thesis yesterday!!! I cried multiple times and can’t put into words how grateful I am to have met Dr. Pachow. He has truly changed my life and will be one of those lifetime friends. One of the best things to come out of grad school. Congrats!! See you soon in SD! 💕
February 28, 2025 at 11:05 PM
Congrats Thai!!! So excited to see his thesis work published in Nature Neuroscience. Take a look at some ground breaking findings in Huntington's disease related to splicing, TDP-43 and m6A RNA modifications.

www.nature.com/articles/s41...
Aberrant splicing in Huntington’s disease accompanies disrupted TDP-43 activity and altered m6A RNA modification - Nature Neuroscience
Nguyen et al. identify TDP-43 and METTL3 as key regulators of disrupted RNA splicing in Huntington’s disease, offering insight into how TDP-43 mislocalization and aberrant m6A RNA modification and loc...
www.nature.com
January 6, 2025 at 6:29 PM
Reposted by Mara Burns
3 reviews on planning, execution, & validation of transcriptomic experiments in neuroscience published in @natureportfolio.bsky.social #NatureNeuroscience.
A MUST READ if you're doing transcriptomics.
3 reviews, an amazing editorial, a beautiful cover – this is the issue of the year!
(mini thread)
December 11, 2024 at 5:04 PM
Hi Bluesky, I’m new to the app and transitioning from X/Twitter. I’m a 5th year grad student in Dr. Leslie Thompsons lab at UCI focusing on the development of Huntingtons disease with an interest in astrocytes. Happy to be here!
December 1, 2024 at 6:49 PM