Can't believe this was 10 years in the making! 🤯

Our work highlights altered information integration as a potential driver of indecisiveness. Huge thanks to everyone involved in the project: Nadescha Trudel, Gita Prabhu, @lhuntneuro.bsky.social, Michael Moutoussis, & Ray Dolan! 🎉

Using MEG 🧠, we can decode updates in evidence strength from wholebrain activity as a late component, decodability peaking around 920 ms. Mirroring the behavioural findings, high-OC participants show reduced decodability in these updates, particularly in mediofrontal regions.

In the behavioural data, we find that when we’re deciding to decide, we overweight the most recent information - we’re calling this update in evidence strength ΔES. These updates tend to nudge us to commit to a decision, but the effect is reduced along the OC spectrum across both samples.

We’re looking at information gathering using behaviour and #MEG in a big online sample (N>5000) and a lab-based sample (N>100) including #OCD and #GAD patients taking a dimensional transdiagnostic approach.