Maartje Westhoff
@maartjewesthoff.bsky.social
Postdoc in the Dixon lab at UCDavis. Studying cardiovascular physiology by using advanced imaging techniques and electrophysiology.
Reposted by Maartje Westhoff
New in @pnas.org: We uncovered that the small protein 14-3-3 acts as critical modulatory protein, orchestrating calcium channel trafficking, and fine-tuning the heart's response to stress signals. @ucdavishealth.bsky.social @ucd-physiology.bsky.social @mcipucd.bsky.social
pnas.org/doi/full/10....
pnas.org/doi/full/10....
14-3-3 promotes sarcolemmal expression of cardiac CaV1.2 and nucleates isoproterenol-triggered channel superclustering | PNAS
The L-type Ca2+ channel (CaV1.2) is essential for cardiac excitation–contraction coupling.
To contribute to the inward Ca2+ flux that drives Ca2+-i...
pnas.org
January 29, 2025 at 2:29 AM
New in @pnas.org: We uncovered that the small protein 14-3-3 acts as critical modulatory protein, orchestrating calcium channel trafficking, and fine-tuning the heart's response to stress signals. @ucdavishealth.bsky.social @ucd-physiology.bsky.social @mcipucd.bsky.social
pnas.org/doi/full/10....
pnas.org/doi/full/10....