Maarten Langen
@maartenlangen.bsky.social
Reposted by Maarten Langen
Protein domains have no single definition, so why stick to one segmentation? 🧩
Instead of forcing structures into rigid classifications, we built AFragmenter. It uses AlphaFold PAE networks for a tuneable approach to domain parsing.
You control the granularity. 👇
🔗 doi.org/10.1093/bioi...
Instead of forcing structures into rigid classifications, we built AFragmenter. It uses AlphaFold PAE networks for a tuneable approach to domain parsing.
You control the granularity. 👇
🔗 doi.org/10.1093/bioi...
November 24, 2025 at 4:01 PM
Protein domains have no single definition, so why stick to one segmentation? 🧩
Instead of forcing structures into rigid classifications, we built AFragmenter. It uses AlphaFold PAE networks for a tuneable approach to domain parsing.
You control the granularity. 👇
🔗 doi.org/10.1093/bioi...
Instead of forcing structures into rigid classifications, we built AFragmenter. It uses AlphaFold PAE networks for a tuneable approach to domain parsing.
You control the granularity. 👇
🔗 doi.org/10.1093/bioi...
Reposted by Maarten Langen
📣 New preprint alert!
Happy to share the first results from our effort to reannotate Pseudomonas #phage proteins of unknown function, using structural bioinformatics.
📄 doi.org/10.1101/2025...
Happy to share the first results from our effort to reannotate Pseudomonas #phage proteins of unknown function, using structural bioinformatics.
📄 doi.org/10.1101/2025...
Fold first, ask later: structure-informed function annotation of Pseudomonas phage proteins
Phages, the viruses of bacteria, harbor an incredibly diverse repertoire of proteins capable of manipulating their bacterial hosts, inspiring many medical and biotechnological applications. However, t...
doi.org
July 21, 2025 at 6:51 AM
📣 New preprint alert!
Happy to share the first results from our effort to reannotate Pseudomonas #phage proteins of unknown function, using structural bioinformatics.
📄 doi.org/10.1101/2025...
Happy to share the first results from our effort to reannotate Pseudomonas #phage proteins of unknown function, using structural bioinformatics.
📄 doi.org/10.1101/2025...
Reposted by Maarten Langen
Hip hip hooray: our #PTM conservation tool FLAMS turns 1 🎂
To celebrate, we have added handy new features to FLAMS web, incl. 3D visualization of hit proteins & PTM sites with known active/binding sites.
Come check it out @ tinyurl.com/flamsweb & let us know what you think!
To celebrate, we have added handy new features to FLAMS web, incl. 3D visualization of hit proteins & PTM sites with known active/binding sites.
Come check it out @ tinyurl.com/flamsweb & let us know what you think!
FLAMS – Find Lysine Acylations & other Modification Sites
www.biw.kuleuven.be
January 28, 2025 at 8:55 AM
Hip hip hooray: our #PTM conservation tool FLAMS turns 1 🎂
To celebrate, we have added handy new features to FLAMS web, incl. 3D visualization of hit proteins & PTM sites with known active/binding sites.
Come check it out @ tinyurl.com/flamsweb & let us know what you think!
To celebrate, we have added handy new features to FLAMS web, incl. 3D visualization of hit proteins & PTM sites with known active/binding sites.
Come check it out @ tinyurl.com/flamsweb & let us know what you think!