m-wilken.bsky.social
@m-wilken.bsky.social
Reposted
A little challenging to focus on science, recently, but David Baker's group has been absolutely killing it with these design applications.

Computational design of serine hydrolases

Blog Post: www.asimov.press/p/ai-enzymes

www.science.org/doi/10.1126/...
Computational design of serine hydrolases
The design of enzymes with complex active sites that mediate multistep reactions remains an outstanding challenge. With serine hydrolases as a model system, we combined the generative capabilities of ...
www.science.org
February 14, 2025 at 5:17 PM