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lyons-lab.bsky.social
@lyons-lab.bsky.social
470 followers 490 following 8 posts
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edinuni-irr.bsky.social
£70 million investment in IRR spinout Trogenix to tackle aggressive cancers.
The funding will enable the rapid advancement of its pipeline of potentially curative cancer therapies across multiple treatment-resistant cancers
regeneration-repair.ed.ac.uk/ps70-million...
@edinnovations.bsky.social
A man in a lab coat stands in a laboratory witht he background lab lit up in purple and blue
October 6, 2025 at 1:00 PM
lyons-lab.bsky.social
www.nature.com/articles/s41...
FBXW7 regulates MYRF levels to control myelin capacity and homeostasis in the adult central nervous system - Nature Communications
The homeostasis of myelin in the central nervous system is highly regulated, but the underlying mechanisms are unclear. Here, the authors show that the FBXW7 protein has a role in constraining myelin ...
www.nature.com
August 21, 2025 at 9:10 PM
Reposted
mariaeichelvogel.bsky.social
Brilliant Kick off day #ISNASN2025
@neurochemistry.org with the best conference views ever 😎
Glad to be part of it #TogetherForScience

If you wanna know more about my work on axons & zebrafish in the @lyons-lab.bsky.social join me during the poster session tmr evening (LBA45) or just reach out 🐠
August 19, 2025 at 8:55 PM
lyons-lab.bsky.social
For those who want a distraction and/ or are interested, here's the latest from the group, led by Phil Braaker

www.nature.com/articles/s41...
Activity-driven myelin sheath growth is mediated by mGluR5 - Nature Neuroscience
Employing pharmacology, genetics and all-optical approaches in zebrafish, Braaker et al. find that neuronal activity influences the growth of myelin sheaths along axons by signaling through metabotrop...
www.nature.com
May 14, 2025 at 11:45 AM
Reposted
scholpplab.bsky.social
The LSI Exeter invites you to join the first UK Zebrafish Meeting, 10/ - 12/9/ @lsiexeter.bsky.social. We are looking for motivated PhD students/ECRs to present their work - as talks and posters. www.exeter.ac.uk/research/ins... . The deadline for the early bird registration is 15/5/. So, be quick!
April 14, 2025 at 12:03 PM
lyons-lab.bsky.social
Fun to have contributed a little to this, led by the team of the incomparable Guoqiang Yu.

Suspect that this will prove to be an immensely popular image analysis platform for interrogation of dynamic signallingl!
www.sciencedirect.com/science/arti...
Fast, accurate, and versatile data analysis platform for the quantification of molecular spatiotemporal signals
Optical recording of intricate molecular dynamics is becoming an indispensable technique for biological studies, accelerated by the development of new…
www.sciencedirect.com
April 8, 2025 at 3:59 PM
Reposted
philiphasel.bsky.social
Our paper on the superficial glia limitans is now published - huge thank you to all co-authors that helped getting this work across the finish line! www.cell.com/cell-reports...
Defining the molecular identity and morphology of glia limitans superficialis astrocytes in vertebrates
Hasel et al. show that molecularly and morphologically specialized astrocytes make up the brain and spinal cord surface, thereby creating the glia limitans superficialis. These astrocytes selectively ...
www.cell.com
February 24, 2025 at 10:44 AM
lyons-lab.bsky.social
Two new opportunities in Edinburgh:

Research technician in our lab
elxw.fa.em3.oraclecloud.com/hcmUI/Candid...

Senior research technician to support the Zebrafish Imaging and Screening Facility
elxw.fa.em3.oraclecloud.com/hcmUI/Candid...
em3.oraclecloud.com
February 24, 2025 at 11:20 AM
lyons-lab.bsky.social
One week to go before application deadlines...

1. Postdoc, investigating how neurons respond to demyelination.
2. Research assistant, investigating how conduction properties are established in neural circuits

elxw.fa.em3.oraclecloud.com/hcmUI/Candid...

elxw.fa.em3.oraclecloud.com/hcmUI/Candid...
elxw.fa.em3.oraclecloud.com
January 27, 2025 at 8:21 AM
lyons-lab.bsky.social
Couple of opportunities up to join the group!
One at postdoc level, but open to senior support path.
One research assistant role.
Please share, or drop a line if you want to learn more!
Or just apply!
Thanks!

elxw.fa.em3.oraclecloud.com/hcmUI/Candid...

elxw.fa.em3.oraclecloud.com/hcmUI/Candid...
January 16, 2025 at 6:41 PM
lyons-lab.bsky.social
First post at this side.

Latest axon diameter action led by Jenea Bin, in collaboration with Nolan, Mobius, Monk, Werner, and Emery labs.

www.biorxiv.org/content/10.1...
Developmental axon diameter growth of central nervous system axons does not depend on ensheathment or myelination by oligodendrocytes
Myelination facilitates the rapid conduction of action potentials along axons. In the central nervous system (CNS), myelinated axons vary over 100-fold in diameter, with conduction speed scaling linea...
www.biorxiv.org
January 11, 2025 at 5:24 PM