Natalia Szulc
@lumirare.com
LumiRare Founder - delivering advanced scientific insights and personalized support for rare disease patients | Scientist at IIMCB in Warsaw exploring the ubiquitin-proteasome system and degrons
https://lumirare.com
https://lumirare.com
Our new preprint is out! We show that the nucleolus can dynamically switch into a proteostasis hub when needed 🔬
Preprint alert! 🚨
We reveal molecular switches that enable the nucleolus to reorganise into a proteostasis hub - coordinating protein quality control with ribosome biogenesis and cross-talk with other stress-responsive organelles.
A big tour de force by the team 💪
www.biorxiv.org/content/10.1...
We reveal molecular switches that enable the nucleolus to reorganise into a proteostasis hub - coordinating protein quality control with ribosome biogenesis and cross-talk with other stress-responsive organelles.
A big tour de force by the team 💪
www.biorxiv.org/content/10.1...
CHIP, VCP, and Nucleolar Gatekeepers Remodel the Nucleolus into a Stress-Responsive Proteostasis Hub
The nucleolus, classically dedicated to ribosome biogenesis, also acts as a stress-responsive proteostasis hub. During heat shock, misfolded proteins accumulate in its granular component (GC), but whe...
www.biorxiv.org
October 6, 2025 at 2:26 PM
Our new preprint is out! We show that the nucleolus can dynamically switch into a proteostasis hub when needed 🔬
🍁 September flew by - two conferences, two cities, and lots of inspiration. I shared my research at Polonium Foundation’s “Science: Polish Perspectives” in Cambridge 🇬🇧, then presented a poster on our DEGRONOPEDIA at the #EYSF2025 in Vilnius 🇱🇹. Now to decide what to implement next in its 2.0 ver 😊
October 3, 2025 at 8:13 PM
🍁 September flew by - two conferences, two cities, and lots of inspiration. I shared my research at Polonium Foundation’s “Science: Polish Perspectives” in Cambridge 🇬🇧, then presented a poster on our DEGRONOPEDIA at the #EYSF2025 in Vilnius 🇱🇹. Now to decide what to implement next in its 2.0 ver 😊
Excited to share DEGRADATOR — the first computer game 🎮 about protein degradation and PROTAC drugs — at #FEBS2025!
Stop by my poster if you’re around — let’s chat science and gameplay.
#FEBSCongress2025
Stop by my poster if you’re around — let’s chat science and gameplay.
#FEBSCongress2025
July 8, 2025 at 7:42 AM
Excited to share DEGRADATOR — the first computer game 🎮 about protein degradation and PROTAC drugs — at #FEBS2025!
Stop by my poster if you’re around — let’s chat science and gameplay.
#FEBSCongress2025
Stop by my poster if you’re around — let’s chat science and gameplay.
#FEBSCongress2025
Proud that our DEGRONOPEDIA tool could contribute to this! 🎉
Pleased to share our latest work and the first manuscript from the Degron Tagging Cluster in the MRC National Mouse Genetics Network. If you work with protein tags, particularly in tissue biology models, this should be of interest:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
www.biorxiv.org
July 3, 2025 at 10:31 AM
Proud that our DEGRONOPEDIA tool could contribute to this! 🎉
Please share!
We have an open postdoc position! Join us to study how ubiquitin ligases and non-canonical modifications regulate protein stability.
🗓️Apply by: 10.03.2025
🔬Start: 01.08.2025 | Warsaw
💰Salary: ~8300 PLN gross
More & apply: tinyurl.com/pokrzywalab-...
Please share! 🚀
🗓️Apply by: 10.03.2025
🔬Start: 01.08.2025 | Warsaw
💰Salary: ~8300 PLN gross
More & apply: tinyurl.com/pokrzywalab-...
Please share! 🚀
February 17, 2025 at 5:15 PM
Please share!
Beyond excited that DEGRADATOR—our computer game delving into protein degradation and PROTCAs—has now been published! 🎉🥳
Give it a try here: degradator-game.com 🎮
Give it a try here: degradator-game.com 🎮
January 10, 2025 at 10:50 PM
Beyond excited that DEGRADATOR—our computer game delving into protein degradation and PROTCAs—has now been published! 🎉🥳
Give it a try here: degradator-game.com 🎮
Give it a try here: degradator-game.com 🎮