Łukasz Bijoch
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lukaszbijoch.bsky.social
Łukasz Bijoch
@lukaszbijoch.bsky.social
10 followers 75 following 2 posts
Neuroscience of addiction and reward processing
The Nencki Institute in Warsaw, Poland
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lukaszbijoch.bsky.social
Spectacular work on psylocybin demonstrating its potential to induce large-scale plasticity in the mouse cortex. Manipulating neural activity during this reorganization allowed for steering those plastic changes, paving the way for engineered circuit reorganization.
www.cell.com/cell/fulltex...
Psilocybin triggers an activity-dependent rewiring of large-scale cortical networks
Psilocybin reshapes brain networks through activity-dependent plasticity, including a weakening of recurrent cortical loops that could underlie its therapeutic effects.
www.cell.com
December 8, 2025 at 2:00 PM
lukaszbijoch.bsky.social
Happy to share my latest scientific input from my postdoctoral training!

BDNF-MMP9 tight interaction on synapse for neuronal plasticity | Science Advances
www.science.org/doi/10.1126/...
BDNF-driven synaptic plasticity requires autocrine matrix metalloproteinase–9 activity
Extracellular protease, MMP-9, controls structural synaptic plasticity by regulating TrkB activation at a single synapse.
www.science.org
September 25, 2025 at 9:05 PM
Reposted by Łukasz Bijoch
neuronsinactionpl.bsky.social
How does the brain rewire itself? The key lies in activity-regulated transcription factors and chromatin modifiers! These molecular players shape synaptic plasticity. Learn more by joining us #NeuronsInAction2025!
📍the Nencki Institute, Warsaw, Poland
📅 27-31 May, 2025
neuronsinaction.nencki.edu.pl
c-Fos positive cell nuclei segmented in the mouse brain. 3D reconstruction from light-sheet microscope imaging.
March 18, 2025 at 5:35 AM