Nodular lymphocyte predominant Hodgkin lymphoma exhibiting characteristic PD1+ T-cell rosettes around tumor cells

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Acute promyelocytic leukemia, Giemsa stain

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Touch preparation of high-grade mullerian serous carcinoma presenting as a large abdominal mass, performed at the time of frozen section. Although not always additive, touch preparations can be a useful adjunct to evaluate tumor morphology intraoperatively

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‘Starry sky’ appearance of Burkitt lymphoma, here involving testicle

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Happy Friday everyone! Extranodal marginal zone lymphoma involving salivary gland, seen forming lymphoepithelial lesions

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Endocervical adenocarcinoma in situ (AIS). While HPV16 is the most frequent subtype detected in AIS, it shows a stronger association with HPV18 relative to high grade squamous lesions.

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Intrauterine perivascular epithelioid tumor (PEComa) exhibiting HMB45 expression by IHC. This lesion was small and lacked atypia or mitotic activity, predicting benign behavior.

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Endometrial clear cell carcinoma exhibits architecture that ranges from papillary to tubulocystic to solid nests. Unlike its cervical counterpart, CCC of the uterine corpus shows no association with in utero exposure to diethylstilbestrol (DES) #pathsky #medsky #pathology #oncology

So-called ‘flame cells’ present in IgA plasma cell myeloma #pathsky #medsky #pathology #oncology

Nice example of nodal marginal zone lymphoma that exhibits plasmacytic differenitation and frequent dutcher bodies #pathsky #medsky #pathology

Sarcina Ventriculi present on gastric biopsy. This gram positive bacteria is notable for its construction in tetrads and its association with delayed gastric emptying, which may be rarely complicated by emphysematous gastritis and gastric perforation. #pathsky #medsky #pathology

Mast cells with atypical spindled morphology forming aggregates within the bone marrow, diagnostic of mastocytosis. In this case, there is coexistent chronic myelomonocytic leukemia (systemic mastocytosis with an associated hematological neoplasm) #pathsky #medsky #pathology