@llama-no-drama.bsky.social
Single-domain antibody development and technology.
Fascinating example of affinity modulation by photocaging of a nanobody. Non-canonical amino acids provide exciting opportunities for protein engineering.
chemistry-europe.onlinelibrary.wiley.com/doi/full/10....
chemistry-europe.onlinelibrary.wiley.com/doi/full/10....
A Light‐Activatable Photocaged Variant of the Ultra‐High Affinity ALFA‐Tag Nanobody
Tag control: Photo-activatable antibodies are a recent addition to the chemical biology toolbox that allow the manipulation of biological processes by antigen-binding with unprecedented spatiotempora....
chemistry-europe.onlinelibrary.wiley.com
January 24, 2025 at 1:28 AM
Fascinating example of affinity modulation by photocaging of a nanobody. Non-canonical amino acids provide exciting opportunities for protein engineering.
chemistry-europe.onlinelibrary.wiley.com/doi/full/10....
chemistry-europe.onlinelibrary.wiley.com/doi/full/10....