Lizzy Smyth
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lizzysmyth.bsky.social
Lizzy Smyth
@lizzysmyth.bsky.social
Oncologist. Cancer Research 👩‍⚕️. Clinical Trials 🧬💊. Oxford Irish. #Oncsky

❓ Should we switch chemotherapy for patients with gastroesophageal cancer after 3 months?

ARMANI trial published in Lancet Oncol today

✔️ Patients who switched to 2L pac/ram after 3m of OxFU had ⬆️ PFS and OS than patients who continued 1L chemo

❌....but also ⬆️ hospital visits & toxicity.
November 19, 2024 at 4:25 PM
👏 Great to see this published!

VESTIGE is a negative randomised trial with an important lesson..

➡️ Give adjuvant FLOT even when there's residual cancer after neoadjuvant chemo.

👀 Looking forward to the translational work

annalsofoncology.org/article/S0923-…
November 14, 2024 at 9:55 PM