Elizabeth Cairns
@lizcairns.bsky.social
Senior biopharma journalist at Endpoints News
⚡ BREAKING: Summit says PD-1xVEGF bispecific ivonsecimab misses overall survival in closely-watched lung cancer study $SMMT
endpts.com/summit-says-...
endpts.com/summit-says-...
Summit says bispecific misses overall survival in closely-watched lung cancer study
Summit Therapeutics' ivonescimab shows 48% PFS benefit but misses OS endpoint in Phase 3 lung cancer trial; drug's regulatory future unclear after mixed EGFR+ NSCLC results.
endpts.com
May 30, 2025 at 10:44 AM
⚡ BREAKING: Summit says PD-1xVEGF bispecific ivonsecimab misses overall survival in closely-watched lung cancer study $SMMT
endpts.com/summit-says-...
endpts.com/summit-says-...
Lilly's oral GLP-1 looks good in diabetes, but the real test is the upcoming obesity readout. Nice piece from @maxgelman.bsky.social here:
Eli Lilly reports first Phase 3 data for oral GLP-1, posting a win in diabetes
Eli Lilly reported the first Phase 3 data for its oral GLP-1 orforglipron Thursday morning, saying the drug succeeded in a type 2 diabetes trial. The drug hit the primary ...
endpts.com
April 17, 2025 at 10:50 AM
Lilly's oral GLP-1 looks good in diabetes, but the real test is the upcoming obesity readout. Nice piece from @maxgelman.bsky.social here:
Pfizer has dropped its obesity pill danuglipron:
In a blow to its obesity pipeline, Pfizer drops oral drug after liver injury case
Pfizer discontinues obesity pill danuglipron after potential drug-induced liver injury in trial patient; company has GIP receptor antagonist PF-07976016 in Phase 2a testing.
endpts.com
April 14, 2025 at 10:47 AM
Pfizer has dropped its obesity pill danuglipron:
I love the FT's health section but every once in a while it posts a bit of a head-scratcher.
March 13, 2025 at 12:50 PM
I love the FT's health section but every once in a while it posts a bit of a head-scratcher.
Zealand finally got its petre partner - and it's *drumroll* Roche!
$1.4B upfront, $5.3 in biobucks. Not bad.
$1.4B upfront, $5.3 in biobucks. Not bad.
Zealand partners with Roche on its amylin analog in a deal worth $5.3B
Zealand Pharma partners with Roche on obesity drug petrelintide in $5.3B deal. Roche pays $1.4B upfront, plans combo studies with CT-388. Companies to split revenues in US/Europe.
endpts.com
March 12, 2025 at 8:15 AM
Zealand finally got its petre partner - and it's *drumroll* Roche!
$1.4B upfront, $5.3 in biobucks. Not bad.
$1.4B upfront, $5.3 in biobucks. Not bad.
The hotly-awaited vepdegestrant data are in from Arvinas and Pfizer, and they're not as good as hoped. My take for @endpts.com
Arvinas, Pfizer’s PROTAC data fall short of expectations in breast cancer
Arvinas/Pfizer's vepdegestrant shows efficacy in mutated breast cancer patients but not in broader population, failing to outperform similar drugs, Phase 3 VERITAC-2 trial show
endpts.com
March 11, 2025 at 10:59 AM
The hotly-awaited vepdegestrant data are in from Arvinas and Pfizer, and they're not as good as hoped. My take for @endpts.com
Reposted by Elizabeth Cairns
There's a huge amount of useful data and raw sentiment in the latest E100 survey that John Carroll, Endpoints Editor and Founder, conducted for Endpoints readers. We heard from 75 top leaders in biopharma on China, Trump the FDA + more: endpts.com/the-endpoint...
The Endpoints 100: The biotech industry braces for Trump 2.0
A survey of 77 biotech executives reveals concerns about FDA changes following Donald Trump's reelection. Martin Makary's nomination as FDA chief has eased some worries, while Robert F. Kennedy Jr.'s ...
endpts.com
December 11, 2024 at 3:18 PM
There's a huge amount of useful data and raw sentiment in the latest E100 survey that John Carroll, Endpoints Editor and Founder, conducted for Endpoints readers. We heard from 75 top leaders in biopharma on China, Trump the FDA + more: endpts.com/the-endpoint...