Lisa Watt
banner
lisawatt.bsky.social
Lisa Watt
@lisawatt.bsky.social
PhD student @ EPFL 🇨🇭 in the Gräff lab 🧠🐁🧬
Epigenetics - Neuroscience - Memory
Reposted by Lisa Watt
🚨 @lisawatt.bsky.social 's paper is out! We uncovered an epigenetic ‘swing’ that tunes how neuronal ensembles capture memories in the brain 🧬🛝🧠. A project that I co-supervised with @graeffjohannes.bsky.social. Kudos to all authors! onlinelibrary.wiley.com/doi/10.1002/...
Manipulating Engram Histone Acetylation Alters Memory Consolidation
The epigenome provides the brain with a nucleus-templated form of plasticity that is of fundamental importance for learning and memory. Of the various types of epigenetic modifications, elevations in....
onlinelibrary.wiley.com
November 3, 2025 at 4:44 PM
Reposted by Lisa Watt
🚨The paper from my postdoc in @graeffjohannes.bsky.social’s lab at @epfl-brainmind.bsky.social is out! We show that memories can be switched on and off by simply changing the « packaging » of DNA in neurons through epigenetic editing. www.nature.com/articles/s41...
Cell-type- and locus-specific epigenetic editing of memory expression - Nature Genetics
CRISPR-based epigenetic editing is used in a cell-type-specific, locus-restricted and temporally controllable manner in the adult mouse brain to modulate memory expression.
www.nature.com
October 29, 2025 at 11:11 AM