Lioba Berndt
@liobanause.bsky.social
RA in Computational Psychiatry & Neuropharmacological Systems • MSc Clinical Neuroscience • BSc Psychology
We’re now busily back-translating to mice to test these predictions alongside some drugs that might help. 🐁
August 6, 2025 at 2:10 PM
We’re now busily back-translating to mice to test these predictions alongside some drugs that might help. 🐁
In-silico pharmacological modelling suggests increasing NMDA receptor gain as a potential therapeutic target, implying NMDA receptor hypofunction as a key driver of sleep alterations in these high-risk individuals.
August 6, 2025 at 2:10 PM
In-silico pharmacological modelling suggests increasing NMDA receptor gain as a potential therapeutic target, implying NMDA receptor hypofunction as a key driver of sleep alterations in these high-risk individuals.
We combine sleep EEG (recorded in the comfort of people’s homes) with Dynamic Causal Modeling to flag mechanisms of synaptic pathology in young people at risk of psychiatric disorders.
August 6, 2025 at 2:10 PM
We combine sleep EEG (recorded in the comfort of people’s homes) with Dynamic Causal Modeling to flag mechanisms of synaptic pathology in young people at risk of psychiatric disorders.
Huge thanks to everyone that made this project possible: Daisy Crawley, Lana Tymchyk, Anna Hall, Jakub Onysk, Tore Erdmann, Elliot Wimmer @elliottwimmer.bsky.social, Isabel Berwian, Agnes Norbury @agnesnorbury.bsky.social and Quentin Huys @docqhuys.bsky.social!
June 20, 2025 at 11:31 AM
Huge thanks to everyone that made this project possible: Daisy Crawley, Lana Tymchyk, Anna Hall, Jakub Onysk, Tore Erdmann, Elliot Wimmer @elliottwimmer.bsky.social, Isabel Berwian, Agnes Norbury @agnesnorbury.bsky.social and Quentin Huys @docqhuys.bsky.social!
I think this paper explains the concept of Computational Psychiatry really well: doi.org/10.1038/nn.4...
Computational psychiatry as a bridge from neuroscience to clinical applications - Nature Neuroscience
The complexity of problems and data in psychiatry requires powerful computational approaches. Computational psychiatry is an emerging field encompassing mechanistic theory-driven models and theoretica...
doi.org
December 10, 2024 at 12:43 PM
I think this paper explains the concept of Computational Psychiatry really well: doi.org/10.1038/nn.4...