Reposted by Lillian Wu
Check out our paper here to find out more about PBRM1’s role in protecting centromere integrity: www.nature.com/articles/s41... I’ve loved working with @kezlane.bsky.social, @thedownslab.bsky.social, @lillianwu.bsky.social and everyone else involved on this project over the last several years!
PBRM1 directs PBAF to pericentromeres and protects centromere integrity - Nature Communications
Centromere fragility can drive tumourigenesis, so protective mechanisms are important. Here, the authors suggest that the PBAF chromatin remodelling complex, which is frequently misregulated in cancer...
www.nature.com
February 28, 2025 at 10:31 PM
Check out our paper here to find out more about PBRM1’s role in protecting centromere integrity: www.nature.com/articles/s41... I’ve loved working with @kezlane.bsky.social, @thedownslab.bsky.social, @lillianwu.bsky.social and everyone else involved on this project over the last several years!