Liam Holt
@liamholt.bsky.social
What does it feel like in a cell? SciComm, Art, Mental Health ScienceSketches.org
However, ATP-dependent cellular activities are essential for condensate growth. These activities, especially actomysosin dynamics, work their magic by reducing elastic confinement for mesoscale condensates.
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October 1, 2023 at 5:35 PM
However, ATP-dependent cellular activities are essential for condensate growth. These activities, especially actomysosin dynamics, work their magic by reducing elastic confinement for mesoscale condensates.
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Our experiments and simulations unveiled that macromolecular crowding has a dule role in condensate formation dynamics: crowding promotes nucleation but inhibits condensate growth.
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October 1, 2023 at 5:35 PM
Our experiments and simulations unveiled that macromolecular crowding has a dule role in condensate formation dynamics: crowding promotes nucleation but inhibits condensate growth.
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To investigate, we developed the synDrops system, an inducible synthetic phase separation system with a well-defined geometry. synDrops enable us to analyze condensate formation kinetics within yeast and mammalian cells and are amenable to simulation.
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October 1, 2023 at 5:34 PM
To investigate, we developed the synDrops system, an inducible synthetic phase separation system with a well-defined geometry. synDrops enable us to analyze condensate formation kinetics within yeast and mammalian cells and are amenable to simulation.
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The cell interior is a highly complex environment! It’s active, crowded at the mesoscale and exhibits viscoelastic properties. But how does this complex intracellular environment impact phase separation within cells?
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October 1, 2023 at 5:33 PM
The cell interior is a highly complex environment! It’s active, crowded at the mesoscale and exhibits viscoelastic properties. But how does this complex intracellular environment impact phase separation within cells?
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Excited to announce our latest @biorxivpreprint!
Mesoscale molecular assembly is favored by the active, crowded cytoplasm
Tong Shu led the charge, with @glenhocky and @Gaurav6032
tinyurl.com/2rrkw7r7
Bluetorial! 1/5
Mesoscale molecular assembly is favored by the active, crowded cytoplasm
Tong Shu led the charge, with @glenhocky and @Gaurav6032
tinyurl.com/2rrkw7r7
Bluetorial! 1/5
October 1, 2023 at 5:33 PM
Excited to announce our latest @biorxivpreprint!
Mesoscale molecular assembly is favored by the active, crowded cytoplasm
Tong Shu led the charge, with @glenhocky and @Gaurav6032
tinyurl.com/2rrkw7r7
Bluetorial! 1/5
Mesoscale molecular assembly is favored by the active, crowded cytoplasm
Tong Shu led the charge, with @glenhocky and @Gaurav6032
tinyurl.com/2rrkw7r7
Bluetorial! 1/5