Congratulations Juan. Really amazing 🤩

Fair.
It is just easier for me to believe that someone tries to get away with something like this than someone actually getting away with it (for now at least). Mind boggling.

Whatever happened here cannot be called peer review imo. I don't know who did worse - the authors or the "reviewers". They even show the frickin map in a main figure.
Crazy that many excellent papers in Structure have to stand next to something like this.

... or a 30S proteasome.

The last one looks like a 26S proteasome (~350Å long) to me. The one before that also seems to be a proteasomal assembly. Hard to say which one but could be a hybrid proteasome (19S one one side of the 20S and PA200 or PA28 on the other side).

Makes sense, thanks for the explanation 🙂

Looking forward to play around with it once available on EMPIAR. It seems ideal to get a grasp on the processing of (pseudo)symmetric complexes with symmetrie breaking interaction partners.

I was surprised to see that the classification was that complicated. Did you try refinement and 3D classifications with or without image alignment in C1 before refining in C16?
Either way this is such a cool processing problem resulting in such a cool structure and story.
Much congrats!

Very nice, congratulations "Danger" Daniel 😆