Xiaolei Liu
lforlymphatics.bsky.social
Xiaolei Liu
@lforlymphatics.bsky.social
Assistant Professor at Temple University, Lymphatic development, lymphatic functions in lymphedema and heart diseases.
Happy holidays from all the members of the Liu Lab. Wrapping up the last work day with beautiful sunset taken by grad student Long Do. Wish everyone enjoy the holiday break, and hope for an exciting 2025!
December 24, 2024 at 2:12 AM
We are hiring postdoc and research assistant to join our team! See ad below for detailed info! Check our recent paper published on Development to know our research doi.org/10.1242/dev.... . And our image is selected to be the cover image!
December 4, 2024 at 4:25 AM
Reposted by Xiaolei Liu
Pleased to share the work of Mitzy Cowdin and others in our lab showing the requirement for the Hippo pathway kinases Lats1 and 2 for endothelial sensing of hemodynamic flow and for vascular remodeling during embryogenesis 🎉🧪

www.biorxiv.org/content/10.1...
Lats1/2 are essential for developmental vascular remodeling and biomechanical adaptation to shear stress
Blood vessels in mammalian embryos develop from initial aggregates of endothelial cell (EC) progenitors, which coordinate the opening and stabilization of central vascular lumens, all while under prog...
www.biorxiv.org
December 2, 2024 at 1:08 PM
Reposted by Xiaolei Liu
Neural Guidance of Lymphatics

#SchwannCell CXCL12⏫ Sprouting/Patterning of CXCR4+ #LymphaticEndothelialCell

Prox1-CreERT2:Cxcr4f/f🐭
⬇️ Lymphatic Valve formation
⬇️ VEGF-C-induced #Lymphangiogenesis

Xiaolei Liu lab Development 2024 @biologists.bsky.social
journals.biologists.com/dev/article-...
November 24, 2024 at 8:31 PM
Thank you so much for highlighting our work!
Terrific first paper from the Liu's lab on the role of CXCL12/CXCR4 signaling in the lymphatic vasculature (and also they got the cover)! Congratulations Xiaolei and many more papers to come

journals.biologists.com/dev/article-...
November 25, 2024 at 11:43 PM