Leif Seute
@leif-seute.bsky.social
ML for science at Heidelberg Institute for Theoretical Studies and Max Planck Institute for Polymer Research
Ever wondered how one can design dynamics into proteins? Check out our work on flexibility conditioned protein structure design at ICML (Poster W-109, Thu. 11am)!
We introduce a flow matching framework for generating protein backbones with custom per-residue flexibility, validated by 300ns of MD.
We introduce a flow matching framework for generating protein backbones with custom per-residue flexibility, validated by 300ns of MD.
1/6 One of the key features of functional proteins is their inherent structural flexibility. In our recent work at #ICML, we introduce flexibility to protein structure design! More in a thread below.
Code / Tutorial: github.com/graeter-grou...
Poster: W-109, Thu 17 Jul 11 a.m. PDT — 1:30 p.m. PDT
Code / Tutorial: github.com/graeter-grou...
Poster: W-109, Thu 17 Jul 11 a.m. PDT — 1:30 p.m. PDT
July 17, 2025 at 4:32 AM
Ever wondered how one can design dynamics into proteins? Check out our work on flexibility conditioned protein structure design at ICML (Poster W-109, Thu. 11am)!
We introduce a flow matching framework for generating protein backbones with custom per-residue flexibility, validated by 300ns of MD.
We introduce a flow matching framework for generating protein backbones with custom per-residue flexibility, validated by 300ns of MD.