Lauren Slosky
@laurenslosky.bsky.social
Neuropharmacologist | Assistant Prof at the University of Minnesota | New PI interested in GPCRs, addiction biology & drug discovery | 🔬 ➡️ 🐭
This biased allosteric modulator (BAM) biases NTSR1 not only toward β-arrestin, but also toward alternative G protein signaling, switching NTSR1 from a Gq/11 preferring receptor to a G12/13 preferring receptor.
Pretty cool 🧪🧠🟦
Pretty cool 🧪🧠🟦
October 27, 2025 at 8:50 PM
This biased allosteric modulator (BAM) biases NTSR1 not only toward β-arrestin, but also toward alternative G protein signaling, switching NTSR1 from a Gq/11 preferring receptor to a G12/13 preferring receptor.
Pretty cool 🧪🧠🟦
Pretty cool 🧪🧠🟦