Reposted by Lauren Davis
Very grateful to be a part in this project now finally published. www.frontiersin.org/journals/imm...
Frontiers | Crosstalk with infant-derived Th17 cells, as well as exposure to IL-22 promotes maturation of intestinal epithelial cells in an enteroid model
www.frontiersin.org
May 19, 2025 at 9:46 PM
Very grateful to be a part in this project now finally published. www.frontiersin.org/journals/imm...
Reposted by Lauren Davis
🚨 We’re featured in @CBCNews!
Our team is using organoids to study how microbes interact with the gut mucus layer, and how this relationship impacts diseases like IBD 💩🔬
📰 Read the full story: www.cbc.ca/news/health/...
#Microbiome #GutHealth #Organoids #IBD
Our team is using organoids to study how microbes interact with the gut mucus layer, and how this relationship impacts diseases like IBD 💩🔬
📰 Read the full story: www.cbc.ca/news/health/...
#Microbiome #GutHealth #Organoids #IBD
How much does your gut health impact your overall health? A lot, doctors say | CBC News
Doctors are tapping into to the emerging field of the gut microbiome to try to treat some diseases differently.
www.cbc.ca
June 2, 2025 at 10:10 PM
🚨 We’re featured in @CBCNews!
Our team is using organoids to study how microbes interact with the gut mucus layer, and how this relationship impacts diseases like IBD 💩🔬
📰 Read the full story: www.cbc.ca/news/health/...
#Microbiome #GutHealth #Organoids #IBD
Our team is using organoids to study how microbes interact with the gut mucus layer, and how this relationship impacts diseases like IBD 💩🔬
📰 Read the full story: www.cbc.ca/news/health/...
#Microbiome #GutHealth #Organoids #IBD
Reposted by Lauren Davis
New paper from our lab! We developed an organoid-based air-liquid interface (ALI) model that produces physiologically relevant intestinal mucus and discovered that EspC has a mucinolytic superpower which enables C. rodentium to degrade mucus. 🧫🦠https://pmc.ncbi.nlm.nih.gov/articles/PMC12054374/
Defining enteric bacterial pathogenesis using organoids: Citrobacter rodentium uses EspC, an atypical mucinolytic protease, to penetrate mouse colonic mucus
Enteric bacterial pathogens pose significant threats to human health; however, the mechanisms by which they infect the mammalian gut in the face of daunting host defenses remain to be fully defined. F...
pmc.ncbi.nlm.nih.gov
May 8, 2025 at 11:45 PM
New paper from our lab! We developed an organoid-based air-liquid interface (ALI) model that produces physiologically relevant intestinal mucus and discovered that EspC has a mucinolytic superpower which enables C. rodentium to degrade mucus. 🧫🦠https://pmc.ncbi.nlm.nih.gov/articles/PMC12054374/
Reposted by Lauren Davis
#weekendreading 🔬
Mitochondria sense bacterial lactate and drive release of neutrophil extracellular traps
@cellpress.bsky.social #microsky
www.cell.com/cell-host-mi...
Mitochondria sense bacterial lactate and drive release of neutrophil extracellular traps
@cellpress.bsky.social #microsky
www.cell.com/cell-host-mi...
Mitochondria sense bacterial lactate and drive release of neutrophil extracellular traps
Historically, neutrophil mitochondria were overlooked as they do not contribute to
energy homeostasis. Wise et al. reveal that neutrophil mitochondria can sense bacterial
persistence in the phagosome ...
www.cell.com
February 28, 2025 at 11:37 AM
#weekendreading 🔬
Mitochondria sense bacterial lactate and drive release of neutrophil extracellular traps
@cellpress.bsky.social #microsky
www.cell.com/cell-host-mi...
Mitochondria sense bacterial lactate and drive release of neutrophil extracellular traps
@cellpress.bsky.social #microsky
www.cell.com/cell-host-mi...