I know. This is sabotage. Hang in there! ❤

This! 100%

We couldn't have asked for a better crew to explore mitochondrial chaos. Huge thanks to the fantastic collaborators that made this possible: @quintanalab.bsky.social, @xinduan.bsky.social, Eli Sanz, Sergi Simó, Nick Marsh-Armstrong, Yang Hu & Derek Welsbie

The amazing Daniela Santamaría-Muñoz led this work!

We show that degeneration in the Ndufs4 optic neuropathy model unfolds in three phases: early immune activation, a cell-autonomous degeneration phase, and a later non-cell-autonomous propagation phase

🤩

Sending a lot of love your way

You guessed it! Gray is DAPI, cyan is Pax6, and magenta is Calretinin. The distinct 3-stripes mark the connections of specific subtypes of amacrine cells

Nice!! Congratulations to all the authors!

We explored the roles of Let-7 in cortical development, and we found a novel mechanism by which Let-7 regulates migration independently of cell fate specification. And this was SO much fun! Don't forget to check out the time-lapse data. It's always my favorite

The best part was getting to collaborate with the amazing Nadean Brown and Ed Levine!