Alex Costa
@labcosta.bsky.social
Editorial Board @PlantCellEnvir, Board of Advisors @New Phytol, and @Facultyopinions
#Calcium #signaling #Arabidopsis #organelles #PCS #imaging
#Calcium #signaling #Arabidopsis #organelles #PCS #imaging
SALICYLIC ACID SENSOR1 reveals the propagation of an SA hormone surge during plant pathogen advance | Science www.science.org/doi/10.1126/...
SALICYLIC ACID SENSOR1 reveals the propagation of an SA hormone surge during plant pathogen advance
Salicylic acid (SA) is a key phytohormone that orchestrates immune responses against pathogens, including Pseudomonas syringae bacteria. The timing and extent of SA accumulation are tightly controlled...
www.science.org
October 11, 2025 at 8:59 AM
SALICYLIC ACID SENSOR1 reveals the propagation of an SA hormone surge during plant pathogen advance | Science www.science.org/doi/10.1126/...
Farewell party for Matteo! After 8 successful years in my lab, he is now ready to begin a new adventure in Sierla’s lab at
@helsinki.fi. Wishing him the best of luck!
@helsinki.fi. Wishing him the best of luck!
September 27, 2025 at 4:38 AM
Farewell party for Matteo! After 8 successful years in my lab, he is now ready to begin a new adventure in Sierla’s lab at
@helsinki.fi. Wishing him the best of luck!
@helsinki.fi. Wishing him the best of luck!
🍕 Pizza day for @lab_costa with our new guests from Spain — Jorge Morello (Miguel Botella lab, Malaga) and Pavel Brito-Gutiérrez (Maite Sanmartín lab, Valencia). Great way to kick things off!
September 12, 2025 at 4:27 PM
🍕 Pizza day for @lab_costa with our new guests from Spain — Jorge Morello (Miguel Botella lab, Malaga) and Pavel Brito-Gutiérrez (Maite Sanmartín lab, Valencia). Great way to kick things off!
Differential regulation of calcium-activated plant kinases in Arabidopsis thaliana 🌱
A fascinating insight into how plants decode Ca²⁺ signals through CPKs — revealing specificity in calcium signaling.
🔗 onlinelibrary.wiley.com/doi/10.1111/...
A fascinating insight into how plants decode Ca²⁺ signals through CPKs — revealing specificity in calcium signaling.
🔗 onlinelibrary.wiley.com/doi/10.1111/...
September 11, 2025 at 4:47 PM
Differential regulation of calcium-activated plant kinases in Arabidopsis thaliana 🌱
A fascinating insight into how plants decode Ca²⁺ signals through CPKs — revealing specificity in calcium signaling.
🔗 onlinelibrary.wiley.com/doi/10.1111/...
A fascinating insight into how plants decode Ca²⁺ signals through CPKs — revealing specificity in calcium signaling.
🔗 onlinelibrary.wiley.com/doi/10.1111/...
Reposted by Alex Costa
Why would anyone want to be a scientist?
"Doing good science requires the utmost exertion of body, mind and spirit, yet is consistently filled with failure and rejection."
journals.biologists.com/jcs/article/...
"Doing good science requires the utmost exertion of body, mind and spirit, yet is consistently filled with failure and rejection."
journals.biologists.com/jcs/article/...
September 7, 2025 at 12:06 PM
Why would anyone want to be a scientist?
"Doing good science requires the utmost exertion of body, mind and spirit, yet is consistently filled with failure and rejection."
journals.biologists.com/jcs/article/...
"Doing good science requires the utmost exertion of body, mind and spirit, yet is consistently filled with failure and rejection."
journals.biologists.com/jcs/article/...
Thrilled to share that Stefano Buratti has been awarded the Fratelli Confalonieri Postdoctoral Fellowship! He'll be joining my lab @LaStatale to develop innovative tools for exploring plant–environment interactions. Congratulations, Stefano!
June 10, 2025 at 6:53 PM
Thrilled to share that Stefano Buratti has been awarded the Fratelli Confalonieri Postdoctoral Fellowship! He'll be joining my lab @LaStatale to develop innovative tools for exploring plant–environment interactions. Congratulations, Stefano!
Reposted by Alex Costa
What started as a 'funky' observation back in 2017 while visiting the lab of @labcosta.bsky.social, and after skilfull execution of Dominic Kuang, Shanna Romand, and many more, now found a home in Current Biology. www.sciencedirect.com/science/arti...
The burning glass effect of water droplets triggers a high light-induced calcium response in the chloroplast stroma
Plants rely on water and light for photosynthesis, but water droplets on leaves can focus light into high-intensity spots, risking photodamage. Excess…
www.sciencedirect.com
May 20, 2025 at 3:21 PM
What started as a 'funky' observation back in 2017 while visiting the lab of @labcosta.bsky.social, and after skilfull execution of Dominic Kuang, Shanna Romand, and many more, now found a home in Current Biology. www.sciencedirect.com/science/arti...
Interested in plant Ca2+ imaging? If you have (or are about to earn) a PhD, consider joining our team at La Statale (UNIMI) as a Postdoc. A great opportunity to grow your expertise in a vibrant research environment!
Feel free to contact me to discuss applications to the MSCA
Feel free to contact me to discuss applications to the MSCA
May 12, 2025 at 9:46 AM
Interested in plant Ca2+ imaging? If you have (or are about to earn) a PhD, consider joining our team at La Statale (UNIMI) as a Postdoc. A great opportunity to grow your expertise in a vibrant research environment!
Feel free to contact me to discuss applications to the MSCA
Feel free to contact me to discuss applications to the MSCA
Quantifying Plant Biology with Fluorescent Biosensors pubmed.ncbi.nlm.nih.gov/40153610/
A very nice Review from Jones' lab www.slcu.cam.ac.uk/people/alexa...
A very nice Review from Jones' lab www.slcu.cam.ac.uk/people/alexa...
April 28, 2025 at 9:16 AM
Quantifying Plant Biology with Fluorescent Biosensors pubmed.ncbi.nlm.nih.gov/40153610/
A very nice Review from Jones' lab www.slcu.cam.ac.uk/people/alexa...
A very nice Review from Jones' lab www.slcu.cam.ac.uk/people/alexa...
Reposted by Alex Costa
Hydrogen Sulfide 🌋👃
modulates Flagellin-Induced Stomatal Immunity 🍃🦠
New preprint led by Denise Scuffi
www.biorxiv.org/content/10.1...
@labcosta.bsky.social @jan-oleniemeier.bsky.social
modulates Flagellin-Induced Stomatal Immunity 🍃🦠
New preprint led by Denise Scuffi
www.biorxiv.org/content/10.1...
@labcosta.bsky.social @jan-oleniemeier.bsky.social
February 20, 2025 at 10:14 AM
Hydrogen Sulfide 🌋👃
modulates Flagellin-Induced Stomatal Immunity 🍃🦠
New preprint led by Denise Scuffi
www.biorxiv.org/content/10.1...
@labcosta.bsky.social @jan-oleniemeier.bsky.social
modulates Flagellin-Induced Stomatal Immunity 🍃🦠
New preprint led by Denise Scuffi
www.biorxiv.org/content/10.1...
@labcosta.bsky.social @jan-oleniemeier.bsky.social
Reposted by Alex Costa
Please read here about our collaborative work with Ag Kudla @uni-muenster.de on the phosphocode of these two Calcium-dependent kinases. With the power of MS-based functional #proteomics www.science.org/doi/10.1126/...
A bi-kinase module sensitizes and potentiates plant immune signaling
Mutual activation of a Ca2+ sensing bi-kinase module potentiates NADPH oxidase activation to facilitate systemic immunity.
www.science.org
February 18, 2025 at 10:24 AM
Please read here about our collaborative work with Ag Kudla @uni-muenster.de on the phosphocode of these two Calcium-dependent kinases. With the power of MS-based functional #proteomics www.science.org/doi/10.1126/...
Reposted by Alex Costa
Wandering what happens to Chlamydomonas chloroplast and cytosolic Ca2+ dynamics in response to different abiotic stresses?
Our latest work about that is out now! 🦠🔬
A big thank to all the people involved @labcosta.bsky.social, Glen Wheeler and Matteo Ballottari.
Our latest work about that is out now! 🦠🔬
A big thank to all the people involved @labcosta.bsky.social, Glen Wheeler and Matteo Ballottari.
Abiotic Stress‐Induced Chloroplast and Cytosolic Ca2+ Dynamics in the Green Alga Chlamydomonas reinhardtii
Ca2+ signalling has a key role in the perception of environmental stimuli and cellular responses to stresses. Here we show that Ca2+ transients in Chlamydomonas are differently triggered by abiotic s...
onlinelibrary.wiley.com
January 24, 2025 at 1:28 PM
Wandering what happens to Chlamydomonas chloroplast and cytosolic Ca2+ dynamics in response to different abiotic stresses?
Our latest work about that is out now! 🦠🔬
A big thank to all the people involved @labcosta.bsky.social, Glen Wheeler and Matteo Ballottari.
Our latest work about that is out now! 🦠🔬
A big thank to all the people involved @labcosta.bsky.social, Glen Wheeler and Matteo Ballottari.
Merry Christmas and Happy New Year from
@labcosta.bsky.social! Wishing you joy, success, and good luck for an amazing 2025!
@labcosta.bsky.social! Wishing you joy, success, and good luck for an amazing 2025!
December 21, 2024 at 5:40 AM
Merry Christmas and Happy New Year from
@labcosta.bsky.social! Wishing you joy, success, and good luck for an amazing 2025!
@labcosta.bsky.social! Wishing you joy, success, and good luck for an amazing 2025!
Honored to celebrate 6 years of collaborating with @PlantCellEnvir as an Associate Editor! Over 130 handled works later, I’m thrilled to receive this certificate of appreciation. Huge thanks to the team and contributors who made this journey so rewarding! 🌱📜
December 16, 2024 at 2:49 PM
Honored to celebrate 6 years of collaborating with @PlantCellEnvir as an Associate Editor! Over 130 handled works later, I’m thrilled to receive this certificate of appreciation. Huge thanks to the team and contributors who made this journey so rewarding! 🌱📜
An old video of calcium waves in Arabidopsis that still looks stunning... 🌱✨ #PlantScience #CalciumWaves"
December 5, 2024 at 12:51 PM
An old video of calcium waves in Arabidopsis that still looks stunning... 🌱✨ #PlantScience #CalciumWaves"
Designing artificial fluorescent proteins and biosensors by genetically encoding molecular rotor-based amino acids
rdcu.be/d1SrQ
rdcu.be/d1SrQ
Designing artificial fluorescent proteins and biosensors by genetically encoding molecular rotor-based amino acids
Nature Chemistry - The toolbox of artificial fluorescent proteins can be expanded by engineering mimics of the molecular rotor-based fluorophore found in the green fluorescent protein (GFP) into...
rdcu.be
November 29, 2024 at 6:01 AM
Designing artificial fluorescent proteins and biosensors by genetically encoding molecular rotor-based amino acids
rdcu.be/d1SrQ
rdcu.be/d1SrQ
Reposted by Alex Costa
November 26, 2024 at 5:22 PM
NEWS & VIEWS: Follow the calcium road: Conserved mechanisms of growth and development in Marchantia polymorpha (Jiawen Chen, Erin Cullen) doi.org/10.1093/plph...
November 25, 2024 at 3:40 PM
NEWS & VIEWS: Follow the calcium road: Conserved mechanisms of growth and development in Marchantia polymorpha (Jiawen Chen, Erin Cullen) doi.org/10.1093/plph...
I am thrilled to have contributed to this publication with Prof. Kohchi Takayuki's lab! 🎉 First author Megumi Iwano
@KyotoU_News
MID1-COMPLEMENTING ACTIVITY regulates cell proliferation & development via Ca²⁺ signaling in Marchantia polymorpha. 🌱
academic.oup.com/plphys/artic...
@KyotoU_News
MID1-COMPLEMENTING ACTIVITY regulates cell proliferation & development via Ca²⁺ signaling in Marchantia polymorpha. 🌱
academic.oup.com/plphys/artic...
November 25, 2024 at 8:01 AM
I am thrilled to have contributed to this publication with Prof. Kohchi Takayuki's lab! 🎉 First author Megumi Iwano
@KyotoU_News
MID1-COMPLEMENTING ACTIVITY regulates cell proliferation & development via Ca²⁺ signaling in Marchantia polymorpha. 🌱
academic.oup.com/plphys/artic...
@KyotoU_News
MID1-COMPLEMENTING ACTIVITY regulates cell proliferation & development via Ca²⁺ signaling in Marchantia polymorpha. 🌱
academic.oup.com/plphys/artic...
Hello dear...I am also here...let's start with this:
Check out this timelapse of growing Arabidopsis leaves expressing a Calcium sensor. Nature's signal in motion! 🌱 #PlantScience #CalciumSignaling #Arabidopsis"
Check out this timelapse of growing Arabidopsis leaves expressing a Calcium sensor. Nature's signal in motion! 🌱 #PlantScience #CalciumSignaling #Arabidopsis"
November 25, 2024 at 6:25 AM
Hello dear...I am also here...let's start with this:
Check out this timelapse of growing Arabidopsis leaves expressing a Calcium sensor. Nature's signal in motion! 🌱 #PlantScience #CalciumSignaling #Arabidopsis"
Check out this timelapse of growing Arabidopsis leaves expressing a Calcium sensor. Nature's signal in motion! 🌱 #PlantScience #CalciumSignaling #Arabidopsis"