Kyo Bin Kang
kyobinkang.bsky.social
Kyo Bin Kang
@kyobinkang.bsky.social
A natural product chemist using mass spec to discover chemical diversities in nature.
Working at Sookmyung Women's University, Seoul, Korea as an associate professor.
A new workhorse has arrived! Our lab installed a Waters Xevo G3 Q/ToF today. Looking forward to play with it for observing metabolites!!
October 29, 2025 at 8:28 AM
Yesterday @roman-bushuiev.bsky.social visited our lab. He gave a seminar talk about his recent work on DreaMS (www.nature.com/articles/s41...), and provided a hands-on training to my lab members. Looking forward to what we will discover using this awesome tool!
August 1, 2025 at 8:37 AM
Participated in the MetabolomeXchange stakeholder meeting, one day before #metabolomics2025. So many valuable discussions!
June 21, 2025 at 9:11 PM
Flying to Prague for #Metabolomics2024, the MetabolomeXchange meeting, and some other things. See you soon dear Metabolomics folks!
June 18, 2025 at 12:52 AM
As Penicillium spp. are well-known producers of antibiotic compounds, we wondered if this effect can 'cross-protect' the other bacteria. We performed tripartite cultures of Penicillium-B. subtilis-(E. coli or Ps. putida), and saw that bacillibactin availability decides who will be dominant. 5/6
May 14, 2025 at 5:41 AM
We wondered why, and we focused on a metabolite induced by coculture - bacillibactin, a siderophore of B. subtilis. We tested a B. subtilis 168 that cannot produce bacillibactin and saw that the inhibitory effect on specialized metabolism was weaker in cases with this strain. 3/6
May 14, 2025 at 5:41 AM
This was an unexpected discovery from our project on 85 Penicillium spp.-B. subtilis cocultures. We expected coculture would boost Penicillium specialized metabolism. However, untargeted metabolomics told us the opposite. Most metabolites showed decreased amount in coculture. 2/6
May 14, 2025 at 5:41 AM
As Penicillium spp. are well-known producers of antibiotic compounds, we wondered if this effect can 'cross-protect' the other bacteria. We performed tripartite cultures of Penicillium-B. subtilis-(E. coli or Ps. putida), and saw that bacillibactin availability decides who will be dominant. 5/n
May 14, 2025 at 5:24 AM
We doubt why, and we focused on a metabolite which was induced by coculture - bacillibactin, a siderophore produced by B. subtilis. We tested a B. subtilis 168 which cannot produce bacillibactin and saw that the inhibitory effect on specialized metabolism was weaker in cases with this strain. 3/n
May 14, 2025 at 5:24 AM
This was an unexpected discovery from our project on 85 Penicillium species-B. subtilis cocultures. We expected that coculture would boost Penicillium specialized metabolism. However, untargeted metabolomics told us the opposite happened. Most metabolites showed decreased amounts in coculture. 2/n
May 14, 2025 at 5:24 AM
Thanks to the KR-FR STARS grant, we could meet up with each other in Paris and Seoul in 2023, which brought us to the others of each one's local socities (KSP and AFERP). Congratulations everyone, especially Sarah, @mehdibeni.bsky.social and @adafede.bsky.social 🎉
April 29, 2025 at 12:12 AM
Oliver Fiehn is giving his plenary lecture on his solution for "making metabolomics great again: the LC-BinBase environment" in the Korea Metabolomics Society annual meeting.
April 4, 2025 at 2:33 AM
In the first plenary session of the Korea Metabolomics Society meeting, Prof. Jonathan Sweedler gave an amazing talk on using mass spec imaging for single cell metabolite analysis!
April 3, 2025 at 3:27 AM
Korea Metabolomic Society annual meeting will start 30 mins later!
April 3, 2025 at 12:22 AM
I and my lab's PhD candidate Huong will present our recent works at the @emn-metsoc.bsky.social webinar on Tuesday 25th, March, at 5 pm KST (8 am UTC). Happy to be invited to this wonderful webinar series!
February 27, 2025 at 3:19 AM
We even put this table in our manuscript, which provides almost every available information on antibodies we used. Please never submit to this journal. I really doubt their expertise.
January 22, 2025 at 1:55 AM
I submitted a manuscript to Pharmaceutical Biology, a @tandfresearch.bsky.social journal. They held it for a year with five-round minor revisions, then rejected it because we did not give UniProtID for epitopes of secondary antibodies, that is unknown to anyone. Are you kidding me??
January 22, 2025 at 1:55 AM
My university opened a new facility equipped with two cutting edge Waters mass specs. SELECT SERIES cyclic IMS and MALDI/DESI multi-reflecting imaging MS! So looking forward to playing woth these machines.
January 14, 2025 at 10:08 AM
After the SIMB NP meeting ended, I, my lab postdoc Eunjin, my colleague Chungsub, and two PhD students from SNU visited the Dorrestein lab and had a very nice scientific discussion. Thank you @pieterdorrestein.bsky.social and Ipsita! It was so fun to be back in the lab.
January 10, 2025 at 6:07 AM
SIMB NP2025 starts with a keynote speach of Nobel Prize laureate Jennifer Doudna. A structure-based discovery of an ancestral CRISPR-Cas13 (doi.org/10.1126/scie...) and a viral proteome study (www.nature.com/articles/s41...) were discussed.
January 6, 2025 at 1:52 AM
Flying to San Diego, for participating in the SIMB Natural Products meeting. My first revisit since 2019.
January 4, 2025 at 6:33 AM
Christmas mood on in my lab 🎄
December 4, 2024 at 8:59 AM
Attending mBiome Conference, a gathering of human microbiome researchers in Korea. Getting a lot of insights for further research plans in my lab.
November 22, 2024 at 4:48 AM
Last week our lab had a joint symposium with the plant-insect interaction & ecology lab led by Youngsung Joo, SNU (jooandlee-eco.weebly.com). Recently we won a grant together. Stay tuned for our collaboration on the ecological function of plant secondary metabolites, powered by metabolomics!
November 20, 2024 at 3:57 AM