Kyle Barlow
@kylebarlow.com
Computational Biologist living in the SF Bay Area. Working in industry in antibody discovery and optimization.
BindCraft: Cool name and architecture, and looks to work pretty well. Uses AlphaFold2 backpropagation to hallucinate protein binders, which also allows for flexibility to be modeled on the side of the target protein.
BindCraft: one-shot design of functional protein binders https://www.biorxiv.org/content/10.1101/2024.09.30.615802v1
BindCraft: one-shot design of functional protein binders https://www.biorxiv.org/content/10.1101/2024.09.30.615802v1
Protein-protein interactions (PPIs) are at the core of all key biological processes. However, the co
www.biorxiv.org
October 2, 2024 at 6:37 PM
BindCraft: Cool name and architecture, and looks to work pretty well. Uses AlphaFold2 backpropagation to hallucinate protein binders, which also allows for flexibility to be modeled on the side of the target protein.