Dr. KRJ
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krjensen.bsky.social
Dr. KRJ
@krjensen.bsky.social
MD, researching precision psychiatry and novel treatments for mood disorders in Copenhagen
The paper provides comprehensive age and gender-stratified norms for all scales. 📨Write to me for the paper (it is paywalled, sorry) doi.org/10.1080/080...
December 28, 2024 at 9:19 PM
😷 😟Important notice: Recent Danish SCL-10 norms from 2020 during the COVID lockdown show unusually high distress levels. This data from an abnormal period isn't suitable as a population norm. I recommend using the gender-specific 2000 norms. #COVID19 #Psychiatry
December 28, 2024 at 9:19 PM
♀️♂️ Gender differences are significant: Women score higher on SCL-10 in the general population and even more pronounced in depression patients. Using non-gender-specific targets risks under-treating men and setting unrealistic goals for women. #GenderMedicine
December 28, 2024 at 9:19 PM
I validated two proposed 6 & 9-item #ADHD symptom scales from the SCL-90R. While they show good internal consistency (ω>0.8), they borrow items from anxiety scales ("Feeling tense"). So, the gender differences we found might reflect anxiety, not ADHD. 👇
December 28, 2024 at 9:19 PM
📊 BSI scales are shorter versions of SCL-90R, measuring symptoms from anxiety to psychoticism. They're just as reliable as the full version - and now have Danish norms! Consider switching if you're still using the long version. #ClinicalResearch
December 28, 2024 at 9:19 PM
Exactly what we thought when we started this project. We hope we have stopped this research avenue and can use our efforts collectively better elsewhere.
December 8, 2024 at 8:57 PM
💡 Conclusion:
LDAEP is not useful as a biomarker for suicide research or prevention in MDD. We need to look elsewhere for approaches to identifying high-risk individuals.
www.sciencedirect.com/science/art...
#Depression #Suicide #Neurobiology #EEG
Loudness dependent auditory evoked potentials and suicidality in depression – A meta-analysis with replication in unmedicated patients
Major Depressive Disorder (MDD) is a risk factor for suicide. Loudness-Dependent Auditory Evoked Potentials (LDAEP) is an electroencephalographic biom…
www.sciencedirect.com
December 7, 2024 at 10:28 PM
For LDAEP, we found:
❌ No association with and past suicide attempts.
❌ No correlation with suicidality.
❌ No association with suicidality during 12 weeks after EEG.
This held true across the meta-analysis, in the independent cohort, and in the updated meta-analysis.
December 7, 2024 at 10:28 PM
We analysed whether LDAEP was associated with:
1️⃣ Past suicide attempts
2️⃣ Current suicidality in patients with MDD
📶 Preregistered meta-analysis: 10 studies
🚹 Independent cohort: 88 unmedicated MDD patients followed for 12 weeks; preregistered analyses.
🔁 Updated our meta-analysis
December 7, 2024 at 10:28 PM