Heterozygous mutations in the Glucocerebrosidase gene ( GBA1 ), encoding the lysosomal hydrolase β-glucocerebrosidase (GCase), are a genetic risk factor for Parkinson’s disease (PD). To explore the pa...

When probed using fluorescence lifetime imaging microscopy (FLIM), the emission from reduced nicotinamide adenine dinucleotide (NADH) and its phosphorylated form NADPH have shown promise as sensitive ...

The autophagy-tethering factor, ectopic P-granule 5 autophagy protein (EPG5), plays a key role in autophagosome-lysosome fusion. Impaired autophagy associated with pathogenic variants in EPG5 cause a ...