kosukeiwai.bsky.social
@kosukeiwai.bsky.social
Excited to announce that our paper is just published in Cell Systems, showing how machine-learning models paired with ultra-high-throughput microfluidic screening can accelerate protein engineering. 

Huge thanks to the fantastic teams at Triplebar, X, The Moonshot Factory and Google DeepMind.
March 13, 2025 at 1:33 AM
Reposted
So proud to see our work on machine learning + enzyme design just published! www.cell.com/cell-systems...

Fun collaboration between Google X, DeepMind, and Triplebar that we hope can be a template for integrating ML and high throughput screening in protein engineering
Engineering highly active nuclease enzymes with machine learning and high-throughput screening
Thomas et al. introduce TeleProt, a framework for guiding protein library design with machine learning, and validate it in an enzyme engineering campaign to optimize the endonuclease NucB. Across 4 ro...
www.cell.com
March 12, 2025 at 5:18 PM