Karolina Mizeracka
@kmizeracka.bsky.social
TPD & induced proximity // drug discovery // Boston biotech
Reposted by Karolina Mizeracka
Delighted to share this timely article in Boston magazine on our local C. elegans community and the effects of NIH freezes.
"There might be no group more enthusiastic, self-aware, or life-affirming than the worm people."
www.bostonmagazine.com/news/c-elega...
"There might be no group more enthusiastic, self-aware, or life-affirming than the worm people."
www.bostonmagazine.com/news/c-elega...
Boston Has Worms (The Good Kind)
Inside the world of C. elegans worms and the scientists who know them best.
www.bostonmagazine.com
May 16, 2025 at 9:29 PM
Delighted to share this timely article in Boston magazine on our local C. elegans community and the effects of NIH freezes.
"There might be no group more enthusiastic, self-aware, or life-affirming than the worm people."
www.bostonmagazine.com/news/c-elega...
"There might be no group more enthusiastic, self-aware, or life-affirming than the worm people."
www.bostonmagazine.com/news/c-elega...
Reposted by Karolina Mizeracka
Congratulations to Kat Kayser-Bricker and the Halda team on leading the efforts to advance RIPTACs to clinic! Also commentary from @danetteldaniels.bsky.social on what this means for the field as well as work being done at Foghorn in this space.
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Induced proximity pushes beyond protein degraders, as first RIPTAC moves into the clinic
Halda Therapeutics has started a clinical trial of its first-in-modality RIPTAC drug HLD-0915 in prostate cancer, to see if bifunctional drugs can provide tissue-specific activity.
www.nature.com
March 3, 2025 at 7:25 PM
Congratulations to Kat Kayser-Bricker and the Halda team on leading the efforts to advance RIPTACs to clinic! Also commentary from @danetteldaniels.bsky.social on what this means for the field as well as work being done at Foghorn in this space.
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Reposted by Karolina Mizeracka
Excited about programming biology via induced proximity? Then mark June 2026 in your calendar and consider participating in the GRC Conference on Induced Proximity Modalities and Therapeutics that I am co-organizing with @danetteldaniels.bsky.social
tinyurl.com/brtuffam
tinyurl.com/brtuffam
January 30, 2025 at 7:32 PM
Excited about programming biology via induced proximity? Then mark June 2026 in your calendar and consider participating in the GRC Conference on Induced Proximity Modalities and Therapeutics that I am co-organizing with @danetteldaniels.bsky.social
tinyurl.com/brtuffam
tinyurl.com/brtuffam
Reposted by Karolina Mizeracka
Thoughts on why DCAF11, DCAF16 and FBXO22 could be the next workhorse E3 ligases in TPD
doi.org/10.1038/s415...
doi.org/10.1038/s415...
Implications of frequent hitter E3 ligases in targeted protein degradation screens - Nature Chemical Biology
This Perspective discusses recent strategies to expand the scope of targeted protein degradation (TPD) and the implications of unexpected convergence of diverse screening efforts on a small subset of ...
doi.org
January 27, 2025 at 8:49 PM
Thoughts on why DCAF11, DCAF16 and FBXO22 could be the next workhorse E3 ligases in TPD
doi.org/10.1038/s415...
doi.org/10.1038/s415...
Reposted by Karolina Mizeracka
So happy to see the growth of our initiative to now offer conference scholarships! Apply below for consideration.
Happy 2025 ☺️☀️☺️
Happy 2025 ☺️☀️☺️
HAPPY HOLIDAYS and EXCITING NEWS!!!
We are offering two conference scholarships for 2025 to early career scientists! One for the Keystone Proximity-Based Therapeutics Conference and one to Frankfurt Conference on Quality Control in Life Processes. Application and details: forms.gle/aP4n7HTujetb...
We are offering two conference scholarships for 2025 to early career scientists! One for the Keystone Proximity-Based Therapeutics Conference and one to Frankfurt Conference on Quality Control in Life Processes. Application and details: forms.gle/aP4n7HTujetb...
Women in TPD & Induced Proximity Conference Scholarship Application
We are thrilled to be offering two conference scholarships in 2025 to early career members of our initiative! Each scholarship will cover the cost of registration and hotel. Awardees will be responsib...
forms.gle
December 23, 2024 at 2:19 PM
So happy to see the growth of our initiative to now offer conference scholarships! Apply below for consideration.
Happy 2025 ☺️☀️☺️
Happy 2025 ☺️☀️☺️