Karen Mohlke
klmohlke.bsky.social
Karen Mohlke
@klmohlke.bsky.social
Reposted by Karen Mohlke
📣New from @klmohlke.bsky.social & co!
📄Skeletal muscle eQTL meta-analysis implicates genes in the genetic architecture of muscular and cardiometabolic traits
www.cell.com/ajhg/fulltex...
Skeletal muscle eQTL meta-analysis implicates genes in the genetic architecture of muscular and cardiometabolic traits
To investigate the underlying mechanisms of complex traits, we performed an eQTL meta-analysis in skeletal muscle and identified 18,818 conditionally distinct signals for 12,283 genes. Colocalization ...
www.cell.com
September 23, 2025 at 5:06 PM
Reposted by Karen Mohlke
I’m excited to share that this manuscript is now published in Nature Genetics! 🧪🧬 🖥️

www.nature.com/articles/s41...

The AdipoExpress data can be accessed here: zenodo.org/records/1384...

An interactive browser of the colocalization results can be accessed here: adipose.colocus.app
January 7, 2025 at 5:45 PM
Reposted by Karen Mohlke
I am excited to share our preprint describing a collaborative effort to identify conditionally distinct signals in the largest adipose eQTL dataset to date (AdipoExpress). @kerrinsmall.bsky.social @klmohlke.bsky.social Laura Scott, and others 🧪🧬 🖥️ #GeneSky 1/8

www.biorxiv.org/content/10.1...
October 27, 2023 at 11:34 PM