Klaus Überla
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Klaus Überla
@klausueberla.bsky.social
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Virus and vaccine research, Head Virology Institute Erlangen, Speaker Research Training Grant "Novel antiviral strategies"
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klausueberla.bsky.social
Our paper on the mechanisms of sterlizing immunity against #HIV was just published at Plos Pathogens: doi.org/10.1371/jour...
Congrats to Elie Richel and many thanks to Christiane Stahl-Hennig for the long and fruitfull collaboration! 🧪 #AIDS
Best way to protect individuals from viruses is to block entry of viruses into the very first cells at the exposed mucosal site. Most important for HIV, since this avoids establishment of latently infected cells, that may reactivate the virus years later. Elie Richel now shows in a preclinical HIV model that monoclonal antibodies can do this this by neutralization, but not by Fc-effector functions.
December 27, 2024 at 9:32 AM