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kichevalab.bsky.social
@kichevalab.bsky.social
Neurodevelopmental lab @ ISTAustria
Patterning, size and growth of neural tube
Huge cheers to @kas-umi.bsky.social for successfully defending her PhD thesis!🎉 We are all so happy to celebrate her achievement, and wish her all the best for her future endeavours👏🙌

Graduate No.4 for the lab😉

#proudmoment
September 9, 2025 at 9:08 AM
Reposted
Always lovely to be in Vienna - wonderful visit yesterday at ISTA. Grateful to everybody who met me and shared their work - it is really a privilege to have a day of amazing science hearing what people are passionate about and learn new things. Thank you so much @kichevalab.bsky.social for having me
June 28, 2025 at 7:35 AM
Our postdoc Rohit Harish just presented his work on the regulation of spinal cord size during mouse development at our internal Neuro Data Talk seminar 👏 Great work, Rohit! We are all looking forward to seeing where your research leads us! 👀🔬🐀
#neurodevelopment #development #spinalcord #neuraltube
June 17, 2025 at 3:50 PM
We are ready for Open Campus at ISTA today 😊
@istaresearch.bsky.social
June 15, 2025 at 10:30 AM
Reposted
New work on dynamics of morphogen signaling:

Cells decode BMP gradient via temporal integration of signaling level, not instantaneous thresholds. While GRN gates response to provide additional spatial input

Morphogen signalling dynamics + GRN for tissue patterning

www.biorxiv.org/content/10.1...
Rapid transcriptional response to a dynamic morphogen by time integration
During development, cells must interpret extracellular signals with speed and accuracy. While morphogen gradients pattern tissues, how cells respond to dynamic morphogens remains unclear. Here, we inv...
www.biorxiv.org
June 10, 2025 at 8:07 AM
Reposted
Good to see this from @kichevalab.bsky.social in final journal format

BMP signalling drives neural tube patterning through a temporal relay mechanism

Lmx1a connects fast negative feedback and slow positive regulation

www.cell.com/developmenta...
Self-organized pattern formation in the developing mouse neural tube by a temporal relay of BMP signaling
Lehr and Brückner et al. develop an in vitro differentiation system that produces self-organized patterns of cell types similar to the ones observed in the dorsal neural tube. They find that to form t...
www.cell.com
February 25, 2025 at 9:07 AM
Reposted
#SYStem2025 :: Vienna, March 12-14 :: #StemCell niches | Deterministic v. stochastic decisions | Germline | Stem cell model systems | #Epigenetics & imprinting | Cell biology of Stem Cells | Transitioning Stem Cells into the clinic; For oral presentations, register by Jan 15! www.sy-stem.org
January 13, 2025 at 10:42 PM